Dosimetry Testing for a New In Vivo X-Ray Fluorescence Measurement System

Details

• Personal Author:
  Burgos CJ ; Grier TR ; Khan M ; Read DE ; Specht AJ ; Taylor KM ; Weisskopf MG
• Description:
  Lead exposure poses severe health risks to individuals, impacting cognitive function, growth, learning, and behavior. Current lead detection methods, primarily blood testing and x-ray fluorescence (XRF) of bone, have limitations. This study introduces a novel in vivo XRF measurement system using K-shell energies of lead, addressing limitations of previous methods. The study aimed to characterize beam directionality, subject radiation dose, and operator occupational exposure. Using a high-energy x-ray tube and room-temperature detectors, various parameters were assessed with bone and tissue phantoms. Dose measurements were taken by altering voltage, current, and shielding. Scatter and spatial measurements highlighted increased scatter with bone and tissue presence, emphasizing the safest positions for bystanders and operators. Results exhibited expected dose rate changes with varying parameters, showcasing the impact of bone and tissue on scatter radiation. The system's total body effective dose (with an 8-mm molybdenum shielding indicating minimal risk compared to established public dose limits) for an adult was 1.94 µSv; for a child aged 10 y, it was 3.28 µSv. This system demonstrates promising capabilities for lead exposure monitoring, offering negligible occupational exposure and minimal risk to individuals being scanned. Its safety and efficacy position it as a valuable tool in assessing lead exposure, potentially improving preventive measures. [Description provided by NIOSH]
• Subjects:
  Biomarkers Lead Occupational Exposure Occupational Health Radiation Dosimeters Safety
• Keywords:
  Author Keywords: Occupational Exposure Dosimetry Exposure Assessment In Vivo Studies Ionizing Radiation Medical Radiation Occupational Exposure Radiotherapy X-ray Fluorescence Analysis
• ISSN:
  0017-9078
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Boston Region [OSHA] ; Chicago Region [OSHA] ; Indiana ; Massachusetts
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  273-278
• Volume:
  128
• Issue:
  4
• NIOSHTIC Number:
  nn:20070595
• Citation:
  Health Phys 2025 Apr; 128(4):273-278
• Contact Point Address:
  Aaron Specht, Purdue University, School of Health Sciences, West Lafayette, IN 47906
• Email:
  aspecht@purdue.edu
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  2025
• Performing Organization:
  Purdue University
• Peer Reviewed:
  True
• Start Date:
  20210901
• Source Full Name:
  Health Physics
• End Date:
  20220731
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6236c739ed718a3f0c2c4fa7222f093c67088eec7b09d8b886d1aa00328a59615564dee634a0b2de794f6969cf0bf4aae2f7c23f11c2b2881cf52aa87674a4bd
• Download URL:
  https://stacks.cdc.gov/view/cdc/208774/cdc_208774_DS1.pdf
• File Type:
  [PDF - 571.85 KB ]