High Rates of Mycobacterium tuberculosis among Socially Marginalized Immigrants in Low-Incidence Area, 1991–2010, Europe

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Baussano, Iacopo ; Mercadante, Silvio ; Pareek, Manish ; Lalvani, Ajit ; Bugiani, Massimiliano
• Description:
  Migration from low- and middle-income countries to high-income countries increasingly determines the severity of tuberculosis (TB) cases in the adopted country. Socially marginalized groups, about whom little is known, may account for a reservoir of TB among the immigrant populations. We investigated the rates of and risk factors for Mycobacterium tuberculosis transmission, infection, and disease in a cohort of 27,358 socially marginalized immigrants who were systematically screened (1991-2010) in an area of Europe with low TB incidence. Overall TB and latent TB infection prevalence and annual tuberculin skin testing conversion rates (i.e., incidence of new infection) were 2.7%, 34.6%, and 1.7%, respectively. Prevalence of both TB and latent TB infection and incidence of infection increased as a function of the estimated TB incidence in the immigrants' countries of origin. Annual infection incidence decreased with time elapsed since immigration. These findings have implications for control policy and immigrant screening in countries with a low prevalence of TB.
• Subjects:
  Adult Bacteria Emigrants And Immigrants Europe Female Humans Immigrants Incidence Latent Tuberculosis Male Mass Screening Mycobacterium Tuberculosis Odds Ratio Prevalence Research Risk Factors Transmission Tuberculosis Tuberculosis And Other Mycobacteria Young Adult

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• Source:
  Emerg Infect Dis. 19(9):1437-1445.
• Document Type:
  Journal Article
• Volume:
  19
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:54a51bd9e857f8e60f483234fdfc7066c069ec1001d22cc21267458fd7719a7a
• Download URL:
  https://stacks.cdc.gov/view/cdc/20874/cdc_20874_DS1.pdf
• File Type:
  [PDF - 723.59 KB ]