Characterizing Dynamic Atmosphere Generation System Performance for Analytical Method Development (Dataset)
Dataset
Public Domain
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2024/12/05
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Series: NIOSH Data
File Language:
English
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Corporate Authors:
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Description:Download the Dataset decsribed here from Data.cdc.gov at https://doi.org/10.26616/NIOSHRD-1100-2024-0.
Laboratory-generated environments are substantial parts of the work involved in developing and validating methods for sampling volatile organic compounds (VOCs) in workplace atmospheres. We assessed the variability of samples produced by our dynamic atmosphere generation system designed for VOC generation and sampling. The characterization of bias and variability was conducted across various atmospheres containing pure n-heptane as well as mixtures of VOCs, which were collected using coconut shell charcoal tubes. The analysis of VOCs from these charcoal tubes was evaluated to reveal the variability from multiple sources: the generation of the atmosphere, the sampling process, and the analytical procedures. This research aimed to quantify the extent of variability from these sources and to estimate the sampling variability associated with our dynamic generation system. Our findings indicated that sampling variability ranged from 2% for pure n-heptane to 12% for a component within a ten-VOC mixture. Notably, sample variability increased with lower concentration levels and in mixtures compared to single-component atmospheres. This study provides a foundational reference for future experiments focused on atmosphere sampling performance at lower concentrations and in mixed VOC environments. [Description provided by NIOSH]
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Media Type:application/zip
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Described By Type:HTML Repository Page
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Rights:Public Domain
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Contact Point:Health Effects Laboratory Division (HELD). Chemical and Biological Monitoring Branch (CBMB)
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Pages in Document:1 ZIP folder
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NIOSHTIC Number:nn:20070367
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Citation:Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Research Dataset RD-1100-2024-0, 2024 Dec; :dataset
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Email:sa-cin-webteam@cdc.gov
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Federal Fiscal Year:2025
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Peer Reviewed:False
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Main Document Checksum:urn:sha-512:428b75c17fe287c9e444d03f42c156ee773439d2eca5071f8d1e979cd7c6c5edeb0555488474243ef5809c2a511dc12b530d5b0a5c67f52e62d6554b51bfb8a3
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File Language:
English
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