Examining Childhood and Adulthood Stressors as Risk Factors for Gestational Diabetes Mellitus in Working Pregnant Individuals: A Prospective Cohort Study

Details

• Personal Author:
  Britt J ; Chen L ; Crockett A ; Hsieh C-T ; Li J ; Mendez L ; Zhang L
• Description:
  Aims: This study aimed to examine the individual and joint associations of adverse childhood experiences (ACEs) and maternal work and non-work related stressors with the risk of gestational diabetes mellitus (GDM). Methods: Working pregnant individuals (n = 1163) from a United States (U.S.) prospective cohort conducted in South Carolina between 2016 and 2021 were included in the study. ACEs were assessed at study enrollment before 20 gestational weeks (GW), while maternal stressors were assessed in late pregnancy and GDM diagnosis occurred between 24 and 30 GW. Multivariable logistic regressions were performed to assess associations of ACEs and maternal stressors with GDM. Results: Childhood abuse, an ACE subdomain, was associated with an elevated but statistically insignificant risk of GDM (adjusted OR = 1.47; 95 % CI: 0.85-2.53). Only maternal work stressors were associated with an increased risk of GDM (adjusted OR = 2.11; 95 % CI: 1.17-3.79) and the association became much stronger among those with childhood abuse experiences (adjusted OR = 3.80; 95 % CI:1.68-8.60). Conclusion: Among U.S. working pregnant individuals, having work stressors during pregnancy was associated with an elevated risk of developing GDM, particularly among those who had childhood experience of abuse. [Description provided by NIOSH]
• Subjects:
  Cohort Studies Mental Health Nervous System Occupational Health Pregnancy Safety Stress, Psychological Violence
• Keywords:
  Abuse Adverse Childhood Experiences Author Keywords: Gestational Diabetes Mellitus Children Cohort Studies Diabetes Job Stress Life-course Perspective Mental Health Occupational Stress Psychosocial Factors Psychosocial Stress

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• ISSN:
  0091-7435
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Atlanta Region [OSHA] ; California ; San Francisco Region [OSHA] ; South Carolina
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  189
• NIOSHTIC Number:
  nn:20070304
• Citation:
  Prev Med 2024 Dec; 189:108163
• Contact Point Address:
  Liwei Chen, Epidemiology, UCLA Fielding School of Public Health, 650 Charles E Young Dr S, Los Angeles, CA 90095, USA
• Email:
  cliwei86@g.ucla.edu
• Federal Fiscal Year:
  2025
• Performing Organization:
  University of California Los Angeles
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Preventive Medicine
• End Date:
  20270630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:471f2a3518c7f7be2d3441b8b86c37812ce83390d8a211c4ceec159aec0400eeee2d50545af48083cd8d3f06174bfc814818021b2bb71d83b26a92986d86f3ac
• Download URL:
  https://stacks.cdc.gov/view/cdc/208543/cdc_208543_DS1.pdf
• File Type:
  [PDF - 692.30 KB ]