Retrospective mortality study of cadmium workers - an update

Details

• Personal Author:
  Halperin, William E. ; Schnorr, Teresa M. ; Thun, Michael J.
• Description:
  A retrospective cohort mortality study was conducted among a group of workers exposed to cadmium (7440439), to determine specific causes of death among these workers. This report reviewed the findings of this study and presented additional findings concerning exposures to other hazards at this facility. The study examined the causes of death for 292 cadmium workers who worked at least 2 years at a small facility that recovered cadmium from bag house dust. Exposures included dusts of cadmium-oxide (1306190) and cadmium- sulfide (1306236) and to fumes of cadmium itself. Over a two fold excess of deaths from respiratory cancer was noted among these workers when compared with the general population and over a three fold excess of deaths from prostatic cancer among the men. A follow up of this study cohort revealed that all cause mortality was slightly below that of the United States male population. The Standardized Mortality Ratio for circulatory disease was 65. Deaths due to respiratory cancer were 65% above the number expected. All of the 20 deaths from respiratory cancer were due to cancer of the lung, trachea and bronchus. Deaths due to genitourinary cancer were 35% above expected levels. The effects of arsenic (7440382) exposure in workers hired prior to 1926 were considered. An over seven fold increase in lung cancer mortality was observed among persons hired prior to 1926. [Description provided by NIOSH]
• Subjects:
  Cadmium Epidemiology Lung Lung Diseases Mortality Neoplasms Occupational Exposure Occupational Health Poisoning Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety

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• Keywords:
  Cadmium-compounds Cadmium-dust Cadmium-poisoning Cancer-rates Lung-cancer Mortality-data Occupational-exposure Risk-factors
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-33
• NIOSHTIC Number:
  nn:00207668
• NTIS Accession Number:
  PB92-205954
• Citation:
  International Lead Zinc Research Organization Fifth International Cadmium Conference, San Francisco, California, February 6, 1986, 1986 Feb; :1-33
• CAS Registry Number:
  Arsenic (CAS RN 7440-38-2) ; Cadmium (CAS RN 7440-43-9) ; Cadmium oxide (CAS RN 1306-19-0) ; Cadmium sulfide (CAS RN 1306-23-6)
• Federal Fiscal Year:
  1986
• Peer Reviewed:
  False
• Source Full Name:
  International Lead Zinc Research Organization Fifth International Cadmium Conference, San Francisco, California, February 6, 1986, 33 pages, 8 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8f3b9aa3f85a6ed82ba15178d9c83024c3da917e03cccd331984cf2553274cd95463bdbfbe0fffe57730304cb3c886dae0d8009fb489507f1efd76a964ffd281
• Download URL:
  https://stacks.cdc.gov/view/cdc/205539/cdc_205539_DS1.pdf
• File Type:
  [PDF - 699.12 KB ]