Mortality of workers employed at organochlorine pesticide manufacturing plants - an update

Details

• Personal Author:
  Brown, David P.
• Description:
  A mortality study on the carcinogenic risk among workers exposed to various organochlorine pesticides was updated from 1976 through 1987. The original study had included white male workers employed for at least 6 months before 31 December 1964 at the four facilities. The workers at the four facilities exposed to the following chemicals: chlordane (57749); heptachlor (76448) and endrin (72208); aldrin (309002), dieldrin (60571), endrin, and dibromochloropropane (96128) (DBCP); and dichlorodiphenyltrichloroethane (50293) (DDT). Four study groups were formed, one from each of the four facilities. The findings supported the possibility of a carcinogenic effect of exposure to organochlorine pesticides. The most important finding was a statistically significant increase in liver and biliary tract cancer among workers at the facility where aldrin, dieldrin, endrin and DBCP were produced. A nonsignificant increase in liver and biliary tract cancer was also noted at the facility where DDT was produced. The lack of exposure data limited the study. [Description provided by NIOSH]
• Subjects:
  Agriculture Bromine Compounds Chlorine Compounds Epidemiology Manufacturing And Industrial Facilities Mortality Neoplasms Occupational Health Risk Assessment Risk Factors Safety

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• Keywords:
  Agricultural-chemicals Author Keywords: Aldrin Cancer Cancer-rates Chemical-industry-workers Chemical-manufacturing-industry Chlordane Dichlorodiphenyltrichloroethane Dieldrin Heptachlor Liver Cancer Mortality-data Mortality-surveys NIOSH-Author Organo-bromine-compounds Organo-chlorine-compounds Organochlorine Pesticides Risk-factors

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• ISSN:
  0355-3140
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  North Carolina ; Ohio ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  155-161
• Volume:
  18
• Issue:
  3
• NIOSHTIC Number:
  nn:00209236
• Citation:
  Scand J Work Environ Health 1992 Jun; 18(3):155-161
• Contact Point Address:
  Mr DP Brown, Office of Occupational Health and Technical Services, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, NC 27709, USA
• CAS Registry Number:
  1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene (CAS RN 57-74-9) ; 1,2-Dibromo-3-chloropropane (CAS RN 96-12-8) ; Aldrin (CAS RN 309-00-2) ; DDT (CAS RN 50-29-3) ; Dieldrin (CAS RN 60-57-1) ; Endrin (CAS RN 72-20-8) ; Heptachlor (CAS RN 76-44-8)
• Federal Fiscal Year:
  1992
• Peer Reviewed:
  True
• Source Full Name:
  Scandinavian Journal of Work, Environment & Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7d8ffca200901a5cec1bf83f9f52a2da8a491244cab652487631fefcf9be5ef17b5f597b56a5055b6a2e355cca2a00a8b4386fd491a041e332f6307e4261d013
• Download URL:
  https://stacks.cdc.gov/view/cdc/205149/cdc_205149_DS1.pdf
• File Type:
  [PDF - 4.04 MB ]