Mortality of workers employed at organochlorine pesticide manufacturing plants - an update.

Details

• Personal Author:
  Brown DP
• Description:
  A mortality study of workers at four organochlorine pesticide manufacturing factories was updated through 1987. The cohorts included all white male workers employed for at least 6 months before December 31, 1964 at the four factories. The workers had been exposed to the following organochlorine pesticides: chlordane (57749), heptachlor (76448), endrin (72208), aldrin (309002), dieldrin (60571), and dichlorodiphenyltrichloroethane (50293) (DDT). Workers at one factory had been exposed to the organobromine pesticide dibromochloropropane (96128). The total number of deaths for the period from 1976 through 1987 was 650. Mortality for all causes and all malignant neoplasms was lower that expected at each of the factories. Cerebrovascular disease mortality was elevated for three of the four factories. The most important result was the statistically significant increase in liver/biliary tract cancer among workers at the facility where aldrin and dieldrin were the primary organochlorine pesticides produced and the nonsignificant increase at the facility where DDT was manufactured.
• Subjects:
  Accidents, Occupational Agriculture Fertilizers Hazardous Substances Manufacturing And Industrial Facilities Occupational Health Preceptorship Safety
• Keywords:
  Agricultural-chemicals Cancer-rates Epidemiology Mortality-data NIOSH-Author Occupational-exposure Organo-chlorine-compounds Pesticide-industry Risk-factors
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Field Studies ; Industry Wide
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-27
• NIOSHTIC Number:
  nn:00211058
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, 1991 Jul; :1-27
• CAS Registry Number:
  1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene (CAS RN 57-74-9) ; Heptachlor (CAS RN 76-44-8) ; Endrin (CAS RN 72-20-8) ; Aldrin (CAS RN 309-00-2) ; Dieldrin (CAS RN 60-57-1) ; DDT (CAS RN 50-29-3) ; 1,2-Dibromo-3-chloropropane (CAS RN 96-12-8)
• Federal Fiscal Year:
  1991
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d5ed8801aaa6c750c9f4f55642db56e5056ce612d94f7469d24b866bdab30703bd8ecc3c7269393ca2ea155885e9ddb433c517fd1e160388933cfd23a67b2e8f
• Download URL:
  https://stacks.cdc.gov/view/cdc/180816/cdc_180816_DS1.pdf
• File Type:
  [PDF - 446.66 KB ]