Information profiles on potential occupational hazards: glycols

Details

• Description:
  Based on their importance in the industrial community, information profiles were provided for the following glycols: 2-butene-1,4-diol (110645), 1,3-butylene-glycol (107880), 1,4-butylene-glycol (110634), 2-butyne-1,4-diol (110656), 1,4-cyclohexanedimethanol (105088), diethylene-glycol (111466), dipropylene-glycol (108612), ethylene-glycol (107211), 2-ethyl-1,3-hexanediol (94962), 1,6- hexanediol (629118), 2,5-hexanediol (2935446), 2-methyl-2-propyl-1,3- propanediol (78262), neopentyl-glycol (126307), 1,5-pentanediol (111295), propylene-glycol (57556), tetraethylene-glycol (112607), triethylene-glycol (112276), 2,2,4-trimethyl-1,3-pentanediol (144194), and tripropylene-glycol (1638160). The acute toxicity of these compounds was characterized by central nervous system depression. Some of the glycols have caused renal damage of varying degrees. Some of the glycols were readily absorbed through the skin. Administration of diethylene-glycol to animals has caused formation of bladder stones. Investigation of possible carcinogenic, teratogenic, reproductive, or mutagenic potentials for these compounds had been very limited. [Description provided by NIOSH]
• Subjects:
  Agriculture Corrosion Electroplating Epoxy Resins Explosions Explosive Agents Hazardous Substances Nervous System Diseases Occupational Health Plastics Safety Urogenital Diseases Urogenital System

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• Keywords:
  Agricultural-chemicals Contract-210-79-0030 Corrosion-inhibitors Explosives Kidney-damage Nervous-system-disorders NIOSH-Contract Plasticizers Resins Toxic-effects
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Final Contract Report
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-208
• NIOSHTIC Number:
  nn:00188286
• NTIS Accession Number:
  PB89-215776
• Citation:
  Center for Chemical Hazard Assessment, Syracuse Research Corporation, Syracuse, New York, 1982 Feb; :1-208
• CAS Registry Number:
  (±)-Propylene glycol (CAS RN 57-55-6) ; 1,1′-[(1-Methyl-1,2-ethanediyl)bis(oxy)]bis-2-propanol (CAS RN 1638-16-0) ; 1,3-Butanediol (CAS RN 107-88-0) ; 1,4-Butanediol (CAS RN 110-63-4) ; 1,4-Cyclohexanedimethanol (CAS RN 105-08-8) ; 1,5-Pentanediol (CAS RN 111-29-5) ; 1,6-Hexanediol (CAS RN 629-11-8) ; 2,2,4-Trimethyl-1,3-pentanediol (CAS RN 144-19-4) ; 2,2′-Oxybis[1-propanol] (CAS RN 108-61-2) ; 2,5-Hexanediol (CAS RN 2935-44-6) ; 2-Butene-1,4-diol (CAS RN 110-64-5) ; 2-Butyne-1,4-diol (CAS RN 110-65-6) ; 2-Methyl-2-propyl-1,3-propanediol (CAS RN 78-26-2) ; Diethylene glycol (CAS RN 111-46-6) ; Ethylene glycol (CAS RN 107-21-1) ; Neopentyl glycol (CAS RN 126-30-7) ; Safrole (CAS RN 94-96-2) ; Tetraethylene glycol (CAS RN 112-60-7) ; Triethylene glycol (CAS RN 112-27-6)
• Federal Fiscal Year:
  1982
• Peer Reviewed:
  False
• Source Full Name:
  Center for Chemical Hazard Assessment, Syracuse Research Corporation, Syracuse, New York, 208 pages, 206 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e751c3d67c26e664c50d155beafb3f1fc02a4a67fe552af4c5ac568d1a3525c0139315caa6822c5d5665cb6c9e6c8d14f12e7a68d8e25ed85f47ea2c941907b7
• Download URL:
  https://stacks.cdc.gov/view/cdc/204942/cdc_204942_DS1.pdf
• File Type:
  [PDF - 5.93 MB ]