Fourier transform infrared spectrometry/attenuated total reflectance study of the reaction of pentanal and propanal with 2-(hydroxymethyl)piperidine

Details

• Personal Author:
  Ashley, Kevin E. ; Kennedy, Eugene R.
• Description:
  The time dependence of the Fourier transform infrared spectrometry (FT-IR) spectra due to the reaction of propanal (123386) and pentanal (110623) with 2-(hydroxymethyl)piperidine and the reaction of pentanal with 2-(ethyl)piperidine were studied. The time resolved FT-IR/attenuated total reflectance attachment (ATR) spectra showed that an oxazolidine derivative was not formed in the initial reaction of the aldehydes with 2-(hydroxymethyl)piperidine. Instead a stable hemiaminal intermediate was noted at the gas/solid interface. In solution this hemiaminal may undergo dehydration to produce an enamine product which is stable. Only after desorption of the intermediate from the sorbent and exposure of the mixture to ultrasound treatment was an oxazolidine formed. In an effort to understand more fully how the coated sorbent interacted with the analyte the contributions of the interplay of adsorption kinetics, reaction rates, and aldehyde volatility must be evaluated. [Description provided by NIOSH]
• Subjects:
  Aldehydes Chemistry Chemistry, Analytic Formaldehyde Occupational Health Safety Solvents Spectrum Analysis
• Keywords:
  Analytical-chemistry Analytical-methods Chemical-analysis Chemical-reactions NIOSH-Author Organic-solvents Solvent-vapors Spectrographic-analysis Volatiles
• ISSN:
  0003-7028
• Document Type:
  Text
• Genre:
  Journal Article
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  266-272
• Volume:
  46
• Issue:
  2
• NIOSHTIC Number:
  nn:00232615
• Citation:
  Appl Spectrosc 1992 Feb; 46(2):266-272
• CAS Registry Number:
  Pentanal (CAS RN 110-62-3) ; Propanal (CAS RN 123-38-6)
• Federal Fiscal Year:
  1992
• Peer Reviewed:
  True
• Source Full Name:
  Applied Spectroscopy
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f91e1c2cceb5aa87cf614eaa161502e758a358620dd480ce2f0b4c9ef71c45188a72b241721d618951ad6fe279bb0602696175bb40d10959b150d05d54e7dd2d
• Download URL:
  https://stacks.cdc.gov/view/cdc/204794/cdc_204794_DS1.pdf
• File Type:
  [PDF - 648.82 KB ]