Molecular characteristics of Staphylococcus aureus isolated from employees, children, and environmental surfaces in Iowa child daycare facilities

Details

• Personal Author:
  Hanson BM ; Kates AE ; Moritz ED ; Smith TC
• Description:
  BACKGROUND: Infectious agents have the potential to thrive in child daycare facilities. Asymptomatic Staphylococcus aureus carriage is a risk factor for developing infection and contributes to transmission. METHODS: We collected swabs from 110 employees, 111 unexposed adults, 81 children, and 214 environmental surfaces at 11 Iowa daycare facilities. S aureus isolates were characterized using antibiotic resistance profiles and Staphylococcal protein A typing. Staphylococcal protein A types were grouped into cluster complexes using the Based Upon Repeat Pattern algorithm. RESULTS: All isolates (from 38 employees, 37 unexposed adults, 16 children, and 19 surfaces) were characterized. Daycare employees were more likely to carry erythromycin-resistant S aureus than unexposed adults (odds ratio, 3.7; 95% confidence interval, 1.1-12.7; P = .033). Isolates were genetically heterogeneous, although isolates from employees appeared more clonal than those from unexposed adults. Strains associated with ST8 were identified in 5 daycare facilities and 3 unexposed adults. CONCLUSIONS: S aureus isolates collected from employees, children, and surfaces of daycare facilities are genetically heterogeneous, but contain strains associated with community-associated methicillin-resistant S aureus. This suggests that daycare facilities can serve as reservoirs for community-associated methicillin-resistant S aureus and facilitate genetic exchange. Employees may be at increased risk of carrying antibiotic-resistant strains, indicating more research is necessary into this occupational group. [Description provided by NIOSH]
• Subjects:
  Anti-Bacterial Agents Antibodies Bacterial Infections Communicable Diseases Genetics Men Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety Women

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• Keywords:
  Antibiotics Antibody-response Asymptomatic Carriage Author Keywords: Antibiotic Resistance Bacteria Bacterial-cultures Bacterial-disease Bacterial-infections CA-MRSA Child-care-workers Children Day-care-facilities Disease-transmission Employee-exposure Genetic-factors Humans Infection-control Infectious-diseases Medicinal-chemicals Occupational Health Proteins Risk-factors Sampling ST8 ST398 Therapeutic-agents

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• ISSN:
  0196-6553
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Iowa ; Maryland ; OSHA Region 3 ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  482-488
• Volume:
  43
• Issue:
  5
• NIOSHTIC Number:
  nn:20046880
• Citation:
  Am J Infect Control 2015 May; 43(5):482-488
• Contact Point Address:
  Erin D. Moritz, PhD, 9315 Gaither Rd, Gaithersburg, MD 20877
• Email:
  moritz.erin@gmail.com
• CAS Registry Number:
  Erythromycin (CAS RN 114-07-8) ; Methicillin (CAS RN 61-32-5)
• Federal Fiscal Year:
  2015
• Performing Organization:
  University of Iowa
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  American Journal of Infection Control
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8b38fb16defa96930d81823414ffb5367b6dae617750cb3a2da04849e785914a7a0aa2f5dd1101a2325a0422cf9dcedf276fbc39464d48c112489608ef2aef2b
• Download URL:
  https://stacks.cdc.gov/view/cdc/202158/cdc_202158_DS1.pdf
• File Type:
  [PDF - 552.29 KB ]