Occupational and neurophysiological deficits in shift work disorder relate to insomnia, not sleepiness

Details

• Personal Author:
  Belcher R ; Drake CL ; Gumenyuk V ; Mengel HJ ; Philport J ; Roth T
• Description:
  Introduction: We examine whether insomnia and excessive sleepiness, the two diagnostic symptoms of Shift Work Disorder (SWD), are differently related to evoked responses and work impairment. Methods: 34 night workers participated in an overnight MSLT and evoked potential assessment. Subjects had no sleep disorders prior to starting night work. At 17:00, each subject completed an Endicott Work Productivity Scale (EWPS), two Insomnia Severity Indices (ISI-Day, ISI-Night), and an Epworth Sleepiness Scale (ESS). Subjects with ISI-Day >/= 10 and ESS < 10 were classified "alert insomniacs" (AI, n = 12). Subjects with ISI-Day >/= 10 and ESS >/= 10 were classified "sleepy insomniacs" (SI, n = 11). Subjects reporting < 10 on both scales were classified controls (n = 11). At 18:00, subjects completed a test of attention to novelty and associated ERPs. Results: Neither the MSLT nor the ESS correlated with EWPS scores or ERP amplitudes (p > .10). However, the mean of the ISI measures correlated with the EWPS (r = .409, p < .01) and the attention-to-novelty P3a (r = -.410, p < .01). The AI group was most impaired on the EWPS, significantly more impaired than controls (25.8 +/- 14.8 vs. 12.3 +/- 9.4, p < .05). SI were not statistically different from controls (19.5 +/- 8.7 vs. 12.3+/- 9.4, p > .05). Interestingly, the fatigue subscale of the EWPS was significantly higher in AI than in controls (6.3 +/- 3.1 vs. 3.4 +/- 2.5, p < .05), while there was no significant difference between SI and controls (4.8 +/- 1.7 vs. 3.4 +/- 3.1, p > .10). Compared to controls, AI showed significantly attenuated P3a responses (Fcz, Czp, Cpz, MD 1.62-1.77, p < .05) and target-detection P3b responses (Fcz, Czp, Cpz, MD 1.28-1.64, p < .05). P3b in SI was not different from controls (p > .10) and P3a was only different at one electrode (Cpz, MD 1.43, p < .01). Conclusion: Insomnia is linked to functional and cognitive impairments in shift workers. Insomniacs with normal sleepiness showed more severe impairments than insomniacs who reported excessive sleepiness. [Description provided by NIOSH]
• Subjects:
  Fatigue Nervous System Occupational Health Safety Shift Work Schedule Sleep Sleep Initiation And Maintenance Disorders Surveys And Questionnaires
• Keywords:
  Analytical-instruments Analytical-models Brain-function Health-surveys Humans Neurophysiological-effects Neurophysiology Physiological-fatigue Physiological-response Shift-work Shift-workers Sleep-deprivation Sleep-disorders Work-intervals Work-performance

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• ISSN:
  0161-8105
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  Michigan ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  37
• NIOSHTIC Number:
  nn:20045424
• Citation:
  Sleep 2014 Mar; 37(Abstract Suppl):A169-A170
• Contact Point Address:
  R. Belcher, Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI, USA
• Federal Fiscal Year:
  2014
• Performing Organization:
  Henry Ford Health System, Detroit, Michigan
• Peer Reviewed:
  False
• Start Date:
  20110901
• Source Full Name:
  Sleep
• Supplement:
  Abstract Supplement
• End Date:
  20140831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:de00f7f3181fe7087897cc83f46046f908e3fdb60d8982f2bb0c440d279e923f37c28a919635e4b15641c988a707ae857c3332987cc0d11e7d6dc619757fae81
• Download URL:
  https://stacks.cdc.gov/view/cdc/200846/cdc_200846_DS1.pdf
• File Type:
  [PDF - 1.51 MB ]