Changes in frequency selectivity in the chinchilla following a noise induced permanent threshold shift

Details

• Personal Author:
  Ahroon WA ; Davis RI ; Hammernik RP
• Description:
  Evoked-potential tuning curves (TC) were obtained on 106 chinchillas before and after acoustic overstimulation in order to assess the effects of the magnitude of hearing loss on frequency selectivity. Pre- and post exposure measures of auditory thresholds and masked thresholds (simultaneous tone-on-tone paradigm) were obtained in each animal at 0.5, 1, 2, 4, 8, and 11.2 kHz, using the evoked auditory response recorded from the inferior colliculus. Three TC variables (Q-10 dB, tail-tip difference, and the high-frequency slope) and sensory cell losses were compared to the amount of noise-induced permanent threshold shift (PTS) produced by a variety of noise exposures. Based upon large sample averages, frequencies showing PTS<20 dB also showed statistically significant differences between pre- and postexposure measures of all three TC variables. For 10 < PTS < 20 dB only the tail-tip difference showed a statistically significant change, while for PTS < 10 dB there were no measurable changes in the TC variables. The percentage of outer hair cell loss showed an orderly and systematic increase as PTS increased and as TC variables changed across the entire range of test frequencies. The inner hair cells were essentially unaffected. These results show that there is a systematic change in the TC variables that define the quality of tuning as hearing loss progressively increases and that these changes are clearly related to outer hair cell losses. [Description provided by NIOSH]
• Subjects:
  Acoustics Animals Environmental Exposure Environmental Pollution Hearing Hearing Loss Laboratories Noise Noise, Occupational Occupational Health Safety Sense Organs Vibration

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• Keywords:
  Acoustic-signals Audiofrequency Cell-function Cellular-function Cellular-reactions Environmental-exposure Environmental-hazards Exposure-levels Hazards Hearing-loss Industrial-noise Laboratory-animals Models Noise-exposure Noise-frequencies Sensory-thresholds Sound Vibration-effects Vibration-exposure

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• ISSN:
  0001-4966
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  83
• NIOSHTIC Number:
  nn:20045148
• Citation:
  J Acoust Soc Am 1988 Mar; 83(Suppl 1):S116
• Federal Fiscal Year:
  1988
• Performing Organization:
  Plattsburgh State University, New York
• Peer Reviewed:
  False
• Start Date:
  19860301
• Source Full Name:
  Journal of the Acoustical Society of America
• Supplement:
  1
• End Date:
  20130514
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0e561d025a6633df3cc518ff37c49888e8506cede1a20958364a11040ec11f46137b0e0452cffc1d16f196e4136c3f25ead6b1aa3b37d4345929e550096d27c5
• Download URL:
  https://stacks.cdc.gov/view/cdc/200668/cdc_200668_DS1.pdf
• File Type:
  [PDF - 157.53 KB ]