Antioxidant Properties of Fruit and Vegetable Juices: More to the Story than Ascorbic Acid

Details

• Personal Author:
  Castranova, Vincent ; Cutler D ; Ding M ; Leonard, Stephen S. ; Shi X ; Vallyathan V
• Description:
  Dietary supplements such as vitamin C have become popular for their perceived ability to enhance the body's antioxidant defenses. Reactive oxygen species (ROS) have been shown to cause a broad spectrum of damage to biological systems. Scavenging of ROS is part of a healthy, well-balanced, antioxidant defense system. The present study used the Fenton reaction as a source of hydroxyl radicals and xanthine/xanthine oxidase as a source of superoxide radicals to investigate the scavenging capabilities of various fruit and vegetable juices against these radicals. Electron spin resonance (ESR) spin trapping was used for free radical detection and measurement. Using a colormetric assay, the present study also investigated the protective effects of fruit and vegetable juices against lipid peroxidation induced in cell membranes by hydroxyl radicals. The present study showed that the free radical scavenging capability of each individual juice, but not its ascorbic acid content, is correlated with its protective effect on free radical induced lipid peroxidation. The results indicate that ascorbic acid is only one facet of the protective effect of fruit and vegetable juices. It appears that consumption of whole fruits and vegetables would be superior to an ascorbic acid supplement for antioxidant effectiveness. [Description provided by NIOSH]
• Subjects:
  Antioxidants Biological Factors Colorimetry Diet Free Radicals Occupational Health Safety
• Keywords:
  Ascorbic Acid Author Keywords: Fruit And Vegetable Juice Biological-effects Biological-factors Biological-systems Dietary-effects Electron Spin Resonance Free-radicals Free Radicals Hydroxyl-groups Lipid-peroxidation Vitamins

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• ISSN:
  0091-7370
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  193-200
• Volume:
  32
• Issue:
  2
• NIOSHTIC Number:
  nn:20022855
• Citation:
  Ann Clin Lab Sci 2002 Nov; 32(2):193-200
• Contact Point Address:
  Xianglin Shi, Ph.D., Pathology and Physiology Research Branch, Health Effects Laboratory Division, NIOSH, Morgantown, WV 26505
• Email:
  xas0@cdc.gov
• Federal Fiscal Year:
  2003
• Peer Reviewed:
  True
• Source Full Name:
  Annals of Clinical and Laboratory Science
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:fd588ca9d666195ef767f6bdd1d083e00299e555af5eaba6ef97dd4a4be93c08f834a0ae94a5c41e99d2481930d6ff5e5b644cd5d68042055451425c13cdde35
• Download URL:
  https://stacks.cdc.gov/view/cdc/199486/cdc_199486_DS1.pdf
• File Type:
  [PDF - 141.70 KB ]