Can Gas Trapping at Low Lung Volumes Reduce Total Lung Capacity?

Details

• Personal Author:
  Frazer DG ; Friend KA ; McKinney WG ; Tomblyn S
• Description:
  In the past we have examined many characteristics of the mechanism responsible for gas trapping in excised lungs [1,2]. Even though there is evidence that gas is trapped during lung inflation [2] and remains trapped at maximum lung volume [3], the effects of gas trapping on the mechanical properties of the lung during expansion are not well understood. The objective of this study was to determine how gas trapped in the lung at low lung volumes 'affects lung expansion by answering the question. "Does" trapped gas aid in holding the lung open by interdependent forces, or does the trapped gas interfere with lung expansion?" In the first case, trapped gas would be expected to reduce the energy required to expand the lung while, in the second case, more energy would be required for lung expansion. [Description provided by NIOSH]
• Subjects:
  Animals Laboratories Lung Occupational Health Respiratory System Safety
• Keywords:
  Animal Studies Gases Laboratory Animals Lung Function Models
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  OSHA Region 3 ; Virginia ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  44
• NIOSHTIC Number:
  nn:20020933
• Citation:
  Proceedings of the 19th Southern Biomedical Engineering Conference, Center for Biomedical Engineering, Virginia Tech, Blacksburg, Virginia, April 14-16, 2000. Arlington, VA: National Science Foundation, 2000 Apr; :44
• Contact Point Address:
  HELD, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  wbg4@cdc.gov
• Federal Fiscal Year:
  2000
• Peer Reviewed:
  False
• Source Full Name:
  Proceedings of the 19th Southern Biomedical Engineering Conference, Center for Biomedical Engineering, Virginia Tech, Blacksburg, Virginia, April 14-16, 2000
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6bb226d5d032443559d21ca057eca444e3ac3c021440d55132e349b172413813df14f2ea8e880784b28f28b596dd776d41e6a16df425ad5112fbb96a91113b16
• Download URL:
  https://stacks.cdc.gov/view/cdc/198558/cdc_198558_DS1.pdf
• File Type:
  [PDF - 175.82 KB ]