Determinants of chlorpyrifos exposures and urinary 3,5,6-trichloro-2-pyridinol levels among termiticide applicators

Details

• Personal Author:
  Deddens JA ; Hines CJ
• Description:
  Introduction: Chlorpyrifos is an organophosphorus insecticide widely used in the United States to control structural termites. It is metabolized in the liver to chlorpyrifos oxon, which is further detoxified to 3,5,6-trichloro-2-pyridinol (TCP) and excreted into the urine. The mean urine elimination half-life of TCP in humans after administration of oral and dermal doses of chlorpyrifos has been estimated to be 26.9 h (2). The aim of this study was to identify significant determinants of chlorpyrifos exposure and urinary TCP that could be used to build predictive exposure models. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Epidemiology Insecticides Occupational Exposure Occupational Health Organophosphates Safety Urine
• Keywords:
  Analytical-models Employee-exposure Exposure-assessment Models Organo-phosphorus-compounds Organo-phosphorus-pesticides Pest-control Pesticide-residues Pesticides Urinalysis Urine-chemistry

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• ISBN:
  9789170456077
• ISSN:
  0346-7821
• Publisher:
  Arbetslivsinstitutet
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  435-437
• Issue:
  10
• NIOSHTIC Number:
  nn:20041295
• Citation:
  Arbete och Halsa 2001 Jun; 2001(10):435-437
• Contact Point Address:
  C. J. Hines, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-14, Cincinnati, OH 45226, USA
• Email:
  chines@cdc.gov
• CAS Registry Number:
  3,5,6-Trichloro-2-pyridinol (CAS RN 6515-38-4) ; Chlorpyrifos (CAS RN 2921-88-2)
• Editor(s):
  Hagsberg M; Knave B; Lillienberg L; Westberg H
• Federal Fiscal Year:
  2001
• Peer Reviewed:
  False
• Source Full Name:
  Arbete och Halsa (X2001 - exposure assessment in epidemiology and practice, June 10-13, 2001, Göteborg, Sweden)
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d9db0152d4586880a933d32333c6c4866db66921227fb6518db1aa2daee8319831c6eeda6f0d193820664fd395accbe55f8e393ddd9936c6c1ff1453f62bbc14
• Download URL:
  https://stacks.cdc.gov/view/cdc/193898/cdc_193898_DS1.pdf
• File Type:
  [PDF - 117.22 KB ]