Study design and methods to investigate inhalation and dermal exposure to polycyclic aromatic compounds and urinary metabolites from asphalt paving workers: research conducted through partnership

Details

• Personal Author:
  Blackburn GR ; Cavallari JM ; Herrick, Robert F. ; Kriech AJ ; McClean MD ; Olsen, Larry D. ; Osborn LV ; Snawder, John E. ; Blackburn GR ; Cavallari JM ; Herrick, Robert F. ; Kriech AJ ; McClean MD ; Olsen, Larry D. ; Osborn LV ; Snawder, John E.
• Description:
  Innovations in science may require crossing traditional boundaries between industry, unions, government, and academia. While such collaborations have the potential to be highly beneficial and productive, opportunities for such collaborations are often missed due to some of the inherent challenges. This collaborative research effort demonstrates an example of how a successful partnership can optimize the ability to answer complicated scientific questions. Specifically, these researchers collaborated to investigate inhalation and dermal exposures to polycyclic aromatic compounds and related urinary metabolites in hot-mix asphalt paving workers. Reported here are details of the partnership process used to create the study design, the review processes, and details of the analytical methodologies employed to help attain the study goals related to the identification of the nature, source, pathway, and biological relevance of exposure during hot-mix asphalt paving operations. The actual results of the study are being prepared for future publications. [Description provided by NIOSH]
• Subjects:
  Biological Factors Chemistry Energy Metabolism Ethylenes Hydrocarbons Hypersensitivity Inhalation Exposure Occupational Health Respiratory System Safety Skin Urine Workplace

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• Keywords:
  Analytical-processes Asphalt-fumes Asphalt-industry Author Keywords: Asphalt Biological-effects Biological-factors Biological-monitoring Biological-systems Chemical-hypersensitivity Chemical-properties Dermal Fumes Inhalants Inhalation Inhalation-studies Metabolic-activation Metabolites Oils Organic-chemicals Organic-compounds Paving Polycyclic Aromatic Compounds Propylenes Sampling Sampling-methods Skin-exposure Skin-irritants Skin-sensitivity Urinary Metabolites Urine-chemistry Work-areas Work-performance Worker-health Workplace-studies

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• ISSN:
  1040-6638
• Document Type:
  Text
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Indiana ; Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology ; DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Pages in Document:
  243-269
• Volume:
  31
• Issue:
  4
• NIOSHTIC Number:
  nn:20039562
• Citation:
  Polycycl Aromat Compd 2011 Aug; 31(4):243-269
• Contact Point Address:
  Linda V. Osborn, Heritage Research Group, 7901 West Morris Street, Indianapolis, Indiana 4623
• Email:
  linda.osborn@heritage-enviro.com
• Federal Fiscal Year:
  2011
• Peer Reviewed:
  True
• Source Full Name:
  Polycyclic Aromatic Compounds
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2de297f39f511e5f0630a063ca5ba20eaaf458f56750828a97a0a313637e3e8711c0e928f974042bc36f509b75c529f13829c5311864d9526ea3a4e16e5e10f2
• Download URL:
  https://stacks.cdc.gov/view/cdc/192755/cdc_192755_DS1.pdf
• File Type:
  [PDF - 229.79 KB ]