Pilot study for the investigation of personal breathing zone and dermal exposure using levels of polycyclic aromatic compounds (PAC) and PAC metabolites in the urine of hot-mix asphalt paving workers

Details

• Personal Author:
  Blackburn GR ; Cavallari JM ; Herrick, Robert F. ; Kriech AJ ; McClean MD ; Olsen, Larry D. ; Osborn LV ; Snawder, John E.
• Description:
  As part of the design of a comprehensive study of hot-mix asphalt paving workers to investigate the relative contribution of personal breathing zone and dermal exposures to polycyclic aromatic compounds, a two-part pilot (Phase I) was performed. The pilot study was important to examine the sources of exposure, the chemical nature of these exposures, and their biological relevance through analysis of biomarkers in urine. Existing, modified, and new sampling and analytical techniques, used in concert with each other, were evaluated to help design the full-scale study (Phase II). Although subject numbers were limited, the air, dermal, and urine sampling, analytical results and field experience provided valuable guidance in the design and implementation of Phase II. An overview of methods used and developed from this study is provided. More details of those methods selected for Phase II are presented in complementary manuscripts. Results of Phase II will be the subject of future publications. [Description provided by NIOSH]
• Subjects:
  Biomarkers Construction Industry Construction Materials Energy Metabolism Hydrocarbons Inhalation Exposure Occupational Health Polycyclic Aromatic Hydrocarbons Respiratory System Safety Skin Urine

  More +
• Keywords:
  Analytical-instruments Analytical-processes Asphalt-cements Asphalt-concretes Asphalt-fumes Author Keywords: Asphalt Paving Biological-effects Breathing Breathing-atmospheres Breathing-zone Construction Construction-materials Construction-workers Dermal Dermatology Inhalants Inhalation Inhalation-studies Metabolites Polycyclic-aromatic-hydrocarbons Polycyclic Aromatic Compounds Road-construction Road-surfacing Sampling Sampling-equipment Sampling-methods Skin-exposure Skin-irritants Urinalysis

  More +
• ISSN:
  1040-6638
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Indiana ; Massachusetts ; Ohio ; OSHA Region 1 ; OSHA Region 3 ; OSHA Region 5 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  173-200
• Volume:
  31
• Issue:
  4
• NIOSHTIC Number:
  nn:20039688
• Citation:
  Polycycl Aromat Compd 2011 Aug; 31(4):173-200
• Contact Point Address:
  Linda V. Osborn, Heritage Research Group, 7901 West Morris Street, Indianapolis, Indiana 46231, USA
• Email:
  linda.osborn@heritage-enviro.com
• Federal Fiscal Year:
  2011
• Peer Reviewed:
  True
• Source Full Name:
  Polycyclic Aromatic Compounds
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:49dbb1c250a64459c63c0bcea3e0162cd6018543db01ceb9e6e03efae82ce9e9cb0d547728ea78e327cb7d8a6481d30a5d2c24105650d7d36a65e0c34c1ffc2e
• Download URL:
  https://stacks.cdc.gov/view/cdc/192842/cdc_192842_DS1.pdf
• File Type:
  [PDF - 663.41 KB ]