Sensitization and Chronic Beryllium Disease Among Workers in Copper-Beryllium Distribution Centers

Details

• Personal Author:
  Deubner, David C. ; Henneberger, Paul K. ; Kent MS ; Kreiss, Kathleen ; Schuler, Christine R. ; Stanton, Marcia L.
• Description:
  Little is known about the risk of sensitization and chronic beryllium disease (CBD) among workers performing limited processing of copper-beryllium alloys downstream of the primary beryllium industry. In this study, we performed a cross-sectional survey of employees at three copper-beryllium alloy distribution centers. One hundred workers were invited to be tested for beryllium sensitization using the beryllium blood lymphocyte proliferation test (BeLPT); a sensitized worker was further evaluated for CBD. Available beryllium mass concentration air sampling data were obtained for characterization of airborne exposure. One participant, who had exposure to other forms of beryllium, was found to be sensitized and to have CBD, resulting in a prevalence of sensitization/CBD of 1% for all tested. The overall prevalence of beryllium sensitization and CBD for workers in these three copper-beryllium alloy distribution centers is lower than for workers in primary beryllium production facilities. [Description provided by NIOSH]
• Subjects:
  Beryllium Environmental Monitoring Hypersensitivity Occupational Diseases Occupational Exposure Occupational Health Risk Assessment Safety
• Keywords:
  Air-sampling Beryllium-compounds Beryllium-disease Diseases Employee-health Employees Occupational-diseases Occupational-exposure Risk-analysis Sensitization Worker-health Workers

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• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  204-211
• Volume:
  48
• Issue:
  2
• NIOSHTIC Number:
  nn:20029616
• Citation:
  J Occup Environ Med 2006 Feb; 48(2):204-211
• Contact Point Address:
  Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, MS H2800, Morgantown, WV 26505, USA
• Email:
  mstanton@cdc.gov
• CAS Registry Number:
  Beryllium (CAS RN 7440-41-7)
• Federal Fiscal Year:
  2006
• NORA Priority Area:
  Research Tools and Approaches: Exposure Assessment Methods
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b49e64b9e75cb160ceeab0fe3fc8501677f120e5ba7e5bc9b7cfcc447e76443b98dad09318799eb5d1e95dbb5f679301418a5dbfc7c7cfbc246c8132b21e076e
• Download URL:
  https://stacks.cdc.gov/view/cdc/190558/cdc_190558_DS1.pdf
• File Type:
  [PDF - 211.21 KB ]