The Global Burden of Disease Due to Occupational Carcinogens

Details

• Personal Author:
  Concha-Barrientos M ; Driscoll T ; Fingerhut, Marilyn A. ; Leigh J ; Nelson DI ; Pruss-Ustun A ; Steenland, Kyle
• Description:
  The worldwide mortality and morbidity from lung cancer, leukemia, and malignant mesothelioma arising from occupational exposures to carcinogens are described. Cases reported in the year 2000 that resulted from relevant past and current exposures are assessed. The proportions of workers exposed to the carcinogens of interest, and their levels of exposure, were estimated using workforce data and the CAREX (CARcinogen EXposure) database. These were combined with relative risk measures (for lung cancer and leukemia) or absolute risk measures (for malignant mesothelioma) to develop estimates of deaths, disability-adjusted life years (DALYs) and attributable fraction (for lung cancer and leukemia). There were an estimated 152,000 deaths (lung cancer: 102,000; leukemia: 7,000; and malignant mesothelioma: 43,000) and nearly 1.6 million DALYS (lung cancer: 969,000; leukemia: 101,000; and malignant mesothelioma: 564,000) due to exposure to occupational carcinogens. Occupational carcinogens are an important cause of death and disability worldwide. [Description provided by NIOSH]
• Subjects:
  Carcinogens Environmental Monitoring Lung Lung Diseases Morbidity Mortality Neoplasms Occupational Diseases Occupational Exposure Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety

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• Keywords:
  Cancer Carcinogenesis Carcinogenicity Diseases Exposure-assessment Lung-cancer Morbidity-rates Mortality-data Mortality-rates Occupational-diseases Occupational-exposure Pulmonary-system-disorders Respiratory-system-disorders Risk-analysis Risk-factors Workers

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  District of Columbia ; Georgia ; Oklahoma ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 6
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OD - Office of the Director
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  419-431
• Volume:
  48
• Issue:
  6
• NIOSHTIC Number:
  nn:20029120
• Citation:
  Am J Ind Med 2005 Dec; 48(6):419-431
• Email:
  timd@health.usyd.edu.au
• Federal Fiscal Year:
  2006
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d8ec7c36ca3a3c8a12841e38ebd9eaac601ff27c1ff6f252de268bd408f7f6a9f56a86f53d062f74e46ad60692677e108901cd5ffc9c206ae9e8dd8de5f0b1f2
• Download URL:
  https://stacks.cdc.gov/view/cdc/190172/cdc_190172_DS1.pdf
• File Type:
  [PDF - 145.81 KB ]