A Nested Case-Control Study of Leukemia and Ionizing Radiation at the Portsmouth Naval Shipyard

Details

• Personal Author:
  Couch, James R. ; Daniels, Robert D. ; Kinnis GM ; Kubale, Travis L. ; Schubauer-Berigan, Mary K. ; Yiin JH
• Description:
  A nested case-control study using conditional logistic regression was conducted to evaluate any exposure-response relationship between external ionizing radiation and leukemia mortality among civilian workers at the Portsmouth (New Hampshire) Naval Shipyard (PNS). The study age-matched 115 leukemia deaths with 420 controls selected from a cohort of 37,853 civilian workers employed at PNS between 1952 and 1992. In addition to badge doses, exposures to work-related medical x-rays (WRX) were included in the analysis, and adjustment was made for solvent exposure. A significant positive association was found between leukemia mortality and level of external radiation exposure, adjusting for sex, radiation worker status, and solvent exposure duration. Solvent exposure was significantly associated with leukemia mortality adjusting for radiation dose, radiation worker status, and sex. [Description provided by NIOSH]
• Subjects:
  Blood Case Reports Demography Environmental Monitoring Occupational Exposure Occupational Health Radiation Safety Sex Characteristics Ships Solvents

  More +
• Keywords:
  Case-studies Demographic-characteristics Exposure-assessment Ionization Ionizing-radiation Leukemogenesis Military-personnel Occupational-exposure Radiation-effects Radiation-exposure Sex-factors Shipyard-industry Shipyard-workers Shipyards Workers

  More +
• ISSN:
  0017-9078
• Document Type:
  Text
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  89
• Issue:
  1
• NIOSHTIC Number:
  nn:20028197
• Citation:
  Health Phys 2005 Jul; 89(1)(Suppl S):S77
• Federal Fiscal Year:
  2005
• Peer Reviewed:
  False
• Source Full Name:
  Health Physics
• Supplement:
  S
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:496285db45075b1f8db183311544ed4e0dc2240b0666b903f2baefe77a82a67be273fa301cfe96e2091a775f9bf3592b3f859a2e46fae7ac31d7eb4b4da66682
• Download URL:
  https://stacks.cdc.gov/view/cdc/189814/cdc_189814_DS1.pdf
• File Type:
  [PDF - 477.64 KB ]