Self-Reported Medical Conditions in Perfluorooctanesulfonyl Fluoride Manufacturing Workers

Details

• Personal Author:
  Alexander BH ; Grice MM ; Hoffbeck R ; Kampa DM
• Description:
  Objective: To evaluate whether some cancers, other conditions, and pregnancy outcomes were related to occupational perfluorooctane sulfonate (PFOS) exposure. Methods: We surveyed current and former employees of a perfluorooctanesulfonyl fluoride production facility, using a self-administered questionnaire to ascertain several cancers and health conditions. Female cohort members also completed a brief pregnancy history. We requested medical records to validate reported melanoma, breast, prostate, and colon cancers. PFOS exposure was estimated based on a job exposure matrix up to the year of the diagnosis of the condition. Results: Of the 1895 eligible participants, 1400 questionnaires were returned. No association was observed between working in a PFOS-exposed job and the risk of any of the surveyed conditions. Conclusion: We observed no association between working in a PFOS-exposed job and several cancers, common health conditions, and birth weight. [Description provided by NIOSH]
• Subjects:
  Chemistry Cytology Demography Environmental Exposure Environmental Health Environmental Monitoring Epidemiology Health Care Facilities Workforce And Services Neoplasms Occupational Exposure Occupational Health Pregnancy Risk Assessment Risk Factors Safety Surveys And Questionnaires Urogenital Diseases Urogenital System Workplace

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• Keywords:
  Biological-effects Biological-systems Breast-cancer Cancer-rates Chemical-properties Demographic-characteristics Environmental-exposure Environmental-factors Exposure-assessment Exposure-levels Exposure-methods Health-surveys Mathematical-models Medical-monitoring Occupational-exposure Occupational-hazards Quantitative-analysis Questionnaires Reproduction Reproductive-system Reproductive-system-disorders Risk-analysis Risk-factors Statistical-analysis Surveillance-programs Work-areas Work-environment Worker-health

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Minnesota ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  49
• Issue:
  7
• NIOSHTIC Number:
  nn:20037597
• Citation:
  J Occup Environ Med 2007 Jul; 49(7):722-729
• Contact Point Address:
  Bruce H. Alexander, PhD, University of Minnesota School of Public Health, Mayo MMC 807, 420 Delaware St. SE, Minneapolis, MN 55455
• Email:
  balex@umn.edu
• Federal Fiscal Year:
  2007
• Performing Organization:
  University of Minnesota Twin Cities
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a494dafdef17e70653af4d941f6508dab6c88e2170e0c2f927ba2e011e3fea1149399e0639d5a0d4520b1bab84d077b7eb0a4c0fceff6cb715bf24354977f3f9
• Download URL:
  https://stacks.cdc.gov/view/cdc/188667/cdc_188667_DS1.pdf
• File Type:
  [PDF - 186.86 KB ]