Trends in the Incidence of Invasive and In Situ Vulvar Carcinoma

Details

• Personal Author:
  Baxter NN ; Durham SB ; Habermann EB ; Judson PL ; Virnig BA
• Description:
  Objective: To characterize the incidence of vulvar carcinoma in situ and vulvar cancer over time. Methods: We used the Surveillance Epidemiology and End Results database to assess trends in the incidence of vulvar cancer over a 28-year period (1973 through 2000) and determined whether there had been a change in incidence over time. Information collected included patient characteristics, primary tumor site, tumor grade, and follow-up for vital status. We calculated the incidence rates by decade of age, used X2 tests to compare demographic characteristics, and tested for trends in incidence over time. Results: A total of 13,176 in situ and invasive vulvar carcinomas were identified; 57% of the women were diagnosed with in situ, 44% with invasive disease. Vulvar carcinoma in situ increased 411% from 1973 to 2000. Invasive vulvar cancer increased 20% during the same period. The incidence rates for in situ and invasive vulvar carcinomas are distributed differently across the age groups. In situ carcinoma incidence increases until the age of 40-49 years and then decreases, whereas invasive vulvar cancer risk increases as a woman ages, increasing more quickly after 50 years of age. Conclusion: The incidence of in situ vulvar carcinoma is increasing. The incidence of invasive vulvar cancer is also increasing but at a much lower rate. [Description provided by NIOSH]
• Subjects:
  Age Factors Aging Cytology Epidemiology Health Care Facilities Workforce And Services Neoplasms Occupational Health Preventive Medicine Risk Assessment Safety Surveys And Questionnaires Urogenital Diseases Urogenital System

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• Keywords:
  Age-factors Age-groups Biological-systems Cancer-rates Cell-biology Disease-incidence Health-surveys In-vitro-study Medical-monitoring Medical-screening Medical-services Medical-treatment Preventive-medicine Prophylaxis Quantitative-analysis Reproductive-system Reproductive-system-disorders Risk-analysis Statistical-analysis

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• ISSN:
  0029-7844
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Minnesota ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  107
• Issue:
  5
• NIOSHTIC Number:
  nn:20037548
• Citation:
  Obstet Gynecol 2006 May; 107(5):1018-1022
• Contact Point Address:
  Patricia L. Judson, MD, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, 420 Delaware Street SE, MMC 395, Minneapolis, MN 55455
• Email:
  judso003@umn.edu
• Federal Fiscal Year:
  2006
• Performing Organization:
  University of Minnesota Twin Cities
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Obstetrics and Gynecology
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f93bc41c24134927fda50307b9509fdbb13357c46b9d58e80b5d63208a977b18efb09d3c4505c7091dbaa69cca39bc567e5541f7da17173a251cd503c8fa808b
• Download URL:
  https://stacks.cdc.gov/view/cdc/188625/cdc_188625_DS1.pdf
• File Type:
  [PDF - 188.49 KB ]