Cigarette Smoking and Pulmonary Diffusing Capacity

Details

• Personal Author:
  Cotes JE ; Ferris BG Jr. ; Van Ganse WF
• Description:
  Cigarette smoking caused a reduction in the diffusing capacity of the lungs for carbon monoxide and a reduction in coefficient of diffusion of carbon monoxide. This implies that cigarette smoking should be considered in prediction equations. The reduction in the diffusing capacity appeared to be due to a change in the volume of blood in the capillaries. This could account for some of the reversible changes observed in ex-cigarette smokers. The membrane component changed more with age. Prediction formulas were developed for diffusing capacity for the ratio, diffusing capacity/alveolar volume, based on age, height, and life-time packs smoked. [Description provided by NIOSH]
• Subjects:
  Age Factors Blood Hematologic Tests Lung Lung Diseases Men Occupational Health Respiratory Function Tests Respiratory System Respiratory Tract Diseases Safety Smokers Tobacco Products Women

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• Keywords:
  Age-factors Biological-effects Blood-samples Blood-serum Cigarette-smoking Humans Mathematical-models Pulmonary-disorders Pulmonary-function-tests Pulmonary-system Pulmonary-system-disorders Respiration Respiratory-function-tests Respiratory-system-disorders Spirometry Vital-capacity

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• ISSN:
  0003-0805
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  30-41
• Volume:
  105
• Issue:
  1
• NIOSHTIC Number:
  nn:20036824
• Citation:
  Am Rev Respir Dis 1972 Jan; 105(1):30-41
• CAS Registry Number:
  Carbon monoxide (CAS RN 630-08-0)
• Federal Fiscal Year:
  1972
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  Harvard University, Boston, Massachusetts
• Peer Reviewed:
  True
• Start Date:
  19701001
• Source Full Name:
  American Review of Respiratory Disease
• End Date:
  19780930
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7cc78d32bddb611215c1f929af73c24a66dc50e99179f56a89cb377467cd7d24fd4ff935828321277e9a734eeb654ec44427b25e0c42be11d8add6c7d466d4c2
• Download URL:
  https://stacks.cdc.gov/view/cdc/188080/cdc_188080_DS1.pdf
• File Type:
  [PDF - 2.92 MB ]