Determination of the Effective Dermal Penetration Barrier pH of Porcine Skin

Details

• Personal Author:
  Brooks JD ; Riviere JE
• Description:
  The purpose of the present analysis was to determine the operational or effective pH of the skin relative to dermal penetration by using an existing QSPeR model and assessing its best model fit as a function of penetrant's log DpH. [Description provided by NIOSH]
• Subjects:
  Acids Chemistry Dermatitis Environmental Monitoring Hypersensitivity Occupational Health Safety Skin Skin Absorption
• Keywords:
  Absorption-rates Acid-mists Chemical-hypersensitivity Chemical-properties Chemical-reactions Dermatology Exposure-assessment Exposure-levels Exposure-methods Skin-absorption Skin-exposure Skin-irritants Skin-sensitivity

  More +
• ISSN:
  0140-7783
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; North Carolina ; OSHA Region 3 ; OSHA Region 4 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  407-410
• Volume:
  32
• Issue:
  4
• NIOSHTIC Number:
  nn:20035716
• Citation:
  J Vet Pharmacol Ther 2009 Aug; 32(4):407-410
• Contact Point Address:
  Dr Jim Riviere, Center for Chemical Toxicology Research and Pharmacokinetics, 4700 Hillsborough Street, North Carolina State University, Raleigh, NC 27606
• Email:
  jim_riviere@ncsu.edu
• Federal Fiscal Year:
  2009
• NORA Priority Area:
  Work Environment and Workforce: Mixed Exposures ; Manufacturing
• Performing Organization:
  North Carolina State University, Raleigh, North Carolina
• Peer Reviewed:
  True
• Start Date:
  20010601
• Source Full Name:
  Journal of Veterinary Pharmacology and Therapeutics
• End Date:
  20100331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a804c0a12a34014e578a6dbbd764d4bcbf048fef4329f278d561169179e4dd4f8b530c5ace0a47da706d61f0f8d035208c932e8e8510c5d23d090878f54c797c
• Download URL:
  https://stacks.cdc.gov/view/cdc/187485/cdc_187485_DS1.pdf
• File Type:
  [PDF - 232.07 KB ]