Modeling, Estimation and Validation of Cotton Dust and Endotoxin Exposures in Chinese Textile Operations

Details

• Personal Author:
  Astrakianakis G ; Camp JE ; Checkoway, Harvey ; Christiani, David C. ; Feng Z ; Seixas, Noah S. ; Thomas DB
• Description:
  In support of an epidemiological study of cancer incidence among cotton textile workers in Shanghai, PRC, historical estimates of exposure to cotton dust and endotoxin were developed for subjects drawn from a cohort of 267,400 female textile workers. A large dataset of historical cotton dust measurements were available from 56 of the study factories. Using these data, a series of models were developed to estimate cotton dust exposure by year, factory and process. Model estimates were validated by comparing with independently collected measurements gathered over a 15 year period and indicated a low relative bias (< 2%) and relative accuracy (+/- 61%). Endotoxin exposures were estimated using the endotoxin content of cotton dust by major processes obtained in five separate surveys in these factories. The validated exposures were assigned to the 7,242 jobs held by the 3,812 study subjects. Among the exposed workers, the mean cumulative exposure levels were 113.8 mg m(-3)*years for cotton dust and 6,707.7 EU m(-3)*years for endotoxin, respectively. The overall correlation among cotton dust and endotoxin exposures for these subjects was r = 0.58. Using an unusually rich set of historical cotton dust measurements, along with independently collected exposure measurements for validation and conversion to endotoxin levels, validated estimates of cumulative exposure were constructed for this large case-cohort study in the textile industry. [Description provided by NIOSH]
• Subjects:
  Dust Endotoxins Gossypium Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Respiratory Tract Diseases Risk Assessment Risk Factors Safety Surveys And Questionnaires Textile Industry Women

  More +
• Keywords:
  Author Keywords: Cotton Dust Cotton-dust Cotton-mill-workers Dust-exposure Dusts Endotoxin Modeling Occupational-exposure Pulmonary-system-disorders Questionnaires Respiratory-system-disorders Retrospective Exposure Risk-analysis Risk-factors Sampling Statistical-analysis Textile-workers Textiles-industry Validation

  More +
• ISSN:
  0003-4878
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1 ; OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  50
• Issue:
  6
• NIOSHTIC Number:
  nn:20032716
• Citation:
  Ann Occup Hyg 2006 Aug; 50(6):573-582
• Contact Point Address:
  George Astrakianakis, Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA
• Email:
  george@ohsah.bc.ca
• Federal Fiscal Year:
  2006
• Performing Organization:
  Harvard University
• Peer Reviewed:
  True
• Start Date:
  19870701
• Source Full Name:
  Annals of Occupational Hygiene
• End Date:
  20220831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c152d1a6fa5713d727508eb1ad8c0f54c95654494e77c38b7e9062d4680890f2b0c9941b6e87db639ebf2754097301be58cff993b04602be4220fb8afe9cd600
• Download URL:
  https://stacks.cdc.gov/view/cdc/186587/cdc_186587_DS1.pdf
• File Type:
  [PDF - 470.52 KB ]