Beryllium: A Modern Industrial Hazard

Details

• Personal Author:
  Day, Gregory A. ; Kreiss, Kathleen ; Schuler, Christine R.
• Description:
  Beryllium exposure can cause a granulomatous lung disease in workers who develop a lymphocyte-mediated sensitization to the metal. Workers in diverse industries are at risk because beryllium's properties are critical to nuclear, aerospace, telecommunications, electronic, metal alloy, biomedical, and semiconductor industries. The occupational air concentration standard's failure to protect beryllium workers is driving many scientific and occupational health advances. These developments include study of bioavailability of different physicochemical forms of beryllium, medical surveillance to show effectiveness of skin protection in preventing sensitization in high-risk processes, gene-environment interaction, transgenic mice for use in experimental research, and risk-based management of industrial exposures in the absence of effective exposure-response information. Beryllium sensitization and disease prevention are paradigms for much broader public health action in both occupational and general population settings. [Description provided by NIOSH]
• Subjects:
  Beryllium Blood Genetics Hypersensitivity Lung Diseases Metals Occupational Health Public Health Respiratory Tract Diseases Safety Skin

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• Keywords:
  Author Keywords: Berylliosis Beryllium-compounds Beryllium-disease Beryllium-poisoning Dermal Exposure Disease-prevention Lung-disorders Lymphocytes Public-health Pulmonary-system-disorders Respiratory-system-disorders Sensitization Skin-exposure Standards

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• ISSN:
  0163-7525
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  259-277
• Volume:
  28
• NIOSHTIC Number:
  nn:20032308
• Citation:
  Annu Rev Public Health 2007 Apr; 28:259-277
• Contact Point Address:
  Kathleen Kreiss, National Institute for Occupational Safety and Health, Division of Respiratory Disease Studies, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  kkreiss@cdc.gov
• CAS Registry Number:
  Beryllium (CAS RN 7440-41-7)
• Federal Fiscal Year:
  2007
• Peer Reviewed:
  True
• Source Full Name:
  Annual Review of Public Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e189e21f8aae1879b4151b28bbd987e78d680d040ec4e3d666a0db47804b20dc4a6f4b1522a3d54761975b67814203f77ab6aed70991774333d5e9d3db99667a
• Download URL:
  https://stacks.cdc.gov/view/cdc/186332/cdc_186332_DS1.pdf
• File Type:
  [PDF - 2.98 MB ]