Unsuspected Dengue and Acute Febrile Illness in Rural and Semi-Urban Southern Sri Lanka

Reller, Megan E.; Bodinayake, Champika; Nagahawatte, Ajith; Devasiri, Vasantha; Kodikara-Arachichi, Wasantha; Strouse, John J.; Broadwater, Anne; Østbye, Truls; de Silva, Aravinda; Woods, Christopher W.

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Unsuspected Dengue and Acute Febrile Illness in Rural and Semi-Urban Southern Sri Lanka

Published Date:

Feb 2012

Source:

Emerg Infect Dis. 18(2):256-263.

[PDF - 193.68 KB]

Details:

Personal Authors:

Reller, Megan E. ; Bodinayake, Champika ; Nagahawatte, Ajith ; Devasiri, Vasantha ; Kodikara-Arachichi, Wasantha ; ... More ▼

Keywords:

[+]

Description:

Dengue virus (DENV), a globally emerging cause of undifferentiated fever, has been documented in the heavily urbanized western coast of Sri Lanka since the 1960s. New areas of Sri Lanka are now being affected, and the reported number and severity of cases have increased. To study emerging DENV in southern Sri Lanka, we obtained epidemiologic and clinical data and acute- and convalescent-phase serum samples from patients >2 years old with febrile illness. We tested paired serum samples for DENV IgG and IgM and serotyped virus by using isolation and reverse transcription PCR. We identified acute DENV infection (serotypes 2, 3, and 4) in 54 (6.3%) of 859 patients. Only 14% of patients had clinically suspected dengue; however, 54% had serologically confirmed acute or past DENV infection. DENV is a major and largely unrecognized cause of fever in southern Sri Lanka, especially in young adults.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

11-0962-F1.gif	image/gif
11-0962-F1.jpg	image/jpeg
11-0962-F2.gif	image/gif
11-0962-F2.jpg	image/jpeg
11-0962_finalR.nxml	text/plain
license.txt	text/plain

No Related Documents.

You May Also Like:

Leptospirosis as Frequent Cause of Acute Febrile Illness in Southern Sri Lanka

Personal Author:

Reller, Megan E.; Bodinayake, Champika; Nagahawatte, Ajith; Devasiri, Vasantha; Kodikara-Arachichi, Wasantha; Strouse, John J.; Flom, Judith E.; Dumler, J. Stephen; Woods, Christopher W.;

Published:

Sep 2011

Source:

Emerg Infect Dis. 17(9):1678-1684.

Description:

To determine the proportion of fevers caused by leptospirosis, we obtained serum specimens and epidemiologic and clinical data from patients in Galle, Sri Lanka, March-October 2007. Immunoglobulin M ELISA was performed on paired serum specimens to di...

File Type:

[PDF - 211.70 KB]
Unsuspected Rickettsioses among Patients with Acute Febrile Illness, Sri Lanka, 2007

Personal Author:

Reller, Megan E.; Bodinayake, Champica; Nagahawatte, Ajith; Devasiri, Vasantha; Kodikara-Arachichi, Wasantha; Strouse, John J.; Flom, Judith E.; Østbye, Truls; Woods, Christopher W.; Dumler, J. Stephen;

Published:

May 2012

Source:

Emerg Infect Dis. 18(5):825-829.

Description:

We studied rickettsioses in southern Sri Lanka. Of 883 febrile patients with paired serum samples, 156 (17.7%) had acute rickettsioses; rickettsioses were unsuspected at presentation. Additionally, 342 (38.7%) had exposure to spotted fever and/or typ...

File Type:

[PDF - 304.86 KB]
Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka

Personal Author:

Siriwardana, H. V. Yamuna D.; Noyes, Harry A.; Beeching, Nicholas J.; Chance, Michael L.; Karunaweera, Nadira D.; Bates, Paul A.;

Published:

Mar 2007

Source:

Emerg Infect Dis. 13(3):476-478.

Description:

To investigate the relationship of cutaneous leishmaniasis isolates from Sri Lanka to known species, we performed DNA sequencing and microsatellite analyses. We identified Leishmania donovani as the agent of Sri Lanka cutaneous leishmaniasis and show...

File Type:

[PDF - 74.26 KB]
New Dengue Virus Type 1 Genotype in Colombo, Sri Lanka

Personal Author:

Tissera, Hasitha A.; Ooi, Eng Eong; Gubler, Duane J.; Tan, Ying; Logendra, Barathy; Wahala, Wahala M.P.B.; de Silva, Aravinda M.; Abeysinghe, M.R. Nihal; Palihawadana, Paba; Gunasena, Sunethra; Tam, Clarence C.; Amarasinghe, Ananda; Letson, G. William; Margolis, Harold S.; De Silva, Aruna Dharshan;

Published:

Nov 2011

Source:

Emerg Infect Dis. 17(11):2053-2055.

Description:

The number of cases and severity of disease associated with dengue infection in Sri Lanka has been increasing since 1989, when the first epidemic of dengue hemorrhagic fever was recorded. We identified a new dengue virus 1 strain circulating in Sri L...

File Type:

[PDF - 237.30 KB]
Severe Dengue Epidemics in Sri Lanka, 2003–2006

Personal Author:

Kanakaratne, Nalaka; Wahala, Wahala M.P.B.; Messer, William B.; Tissera, Hasitha A.; Shahani, Aruna; Abeysinghe, Nihal; de Silva, Aravinda M.; Gunasekera, Maya;

Published:

Feb 2009

Source:

Emerg Infect Dis. 15(2):192-199.

Description:

Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003-2006) and past (1980-1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been co...

File Type:

[PDF - 439.91 KB]