Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Reller, Megan E. ; Bodinayake, Champika ; Nagahawatte, Ajith ; Devasiri, Vasantha ; Kodikara-Arachichi, Wasantha ; ... More +
Reller, Megan E. ; Bodinayake, Champika ; Nagahawatte, Ajith ; Devasiri, Vasantha ; Kodikara-Arachichi, Wasantha ; Strouse, John J. ; Broadwater, Anne ; Østbye, Truls ; de Silva, Aravinda ; Woods, Christopher W. ; Less -
Description:
Dengue virus (DENV), a globally emerging cause of undifferentiated fever, has been documented in the heavily urbanized western coast of Sri Lanka since the 1960s. New areas of Sri Lanka are now being affected, and the reported number and severity of cases have increased. To study emerging DENV in southern Sri Lanka, we obtained epidemiologic and clinical data and acute- and convalescent-phase serum samples from patients >2 years old with febrile illness. We tested paired serum samples for DENV IgG and IgM and serotyped virus by using isolation and reverse transcription PCR. We identified acute DENV infection (serotypes 2, 3, and 4) in 54 (6.3%) of 859 patients. Only 14% of patients had clinically suspected dengue; however, 54% had serologically confirmed acute or past DENV infection. DENV is a major and largely unrecognized cause of fever in southern Sri Lanka, especially in young adults.
Subject:
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Acute Dengue
Acute Febrile Illness
Adolescent
Adult
Aedes Aegypti
Aged
Antibodies, Viral
Child
Child, Preschool
Cohort Studies
Dengue
Dengue Virus
Female
Fever
Humans
Male
Middle Aged
Molecular Typing
Mosquitoes
Pandemic
Recurrent Dengue
Research
Rural
Rural Population
Secondary Dengue
Semi-urban
Serotyping
Sri Lanka
Sri Lanka. Dengue Hemorrhagic Fever
Suburban Population
Vector-borne Diseases
Viruses
Young Adult
Young Adults
Dengue

Source:
Emerg Infect Dis. 18(2):256-263.
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:1b113dddd1827d4dea5fcbea45f8dc59668ba975b042e9fedc7b7c47ecbc3854
File Type:

Supporting Files

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