A prospective analysis of the potential risk associated with inhalation of aflatoxin-contaminated grain dusts.

Details

• Personal Author:
  Baxter CS ; Burg HE ; Baxter CS ; Burg HE
• Description:
  A prospective analysis of the potential risk associated with inhalation of grain dusts contaiminated with aflatoxins was conducted. The literature concerning the absorption and carcinogenic effects of benzo(a)pyrene (50328) when adsorbed onto respirable particles is reviewed. Similarities and differences between the absorption mechanisms of aflatoxins and benzo(a)pyrene, the metabolic capability of cultured human bronchus towards aflatoxins, and the irritant nature of respired organic dusts are considered. Potential modifying factors known to influence carcinogenic outcome are described. A lack of epidemiological studies of populations exposed to aflatoxins by inhalation is noted. The authors conclude that the health hazard for inhalation of grain dust contaminated with aflatoxins cannot be assessed adequately due to lack of data. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Dust Environmental Health Environmental Pollution Occupational Health Safety Surveys And Questionnaires
• Keywords:
  Air-contamination Dust-exposure Dust-inhalation Environmental-contamination Environmental-factors Health-surveys NIOSH-Grant NIOSH-Publication Organic-dusts
• ISSN:
  0015-6264
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Volume:
  19
• Issue:
  6
• NIOSHTIC Number:
  nn:00126858
• Citation:
  Food Cosmet Toxicol 1981 Jan; 19(6):765-769
• Contact Point Address:
  Environmental Health Kettering Laboratory 3223 Eden Avenue Cincinnati, Ohio 45267
• CAS Registry Number:
  Benzo[a]pyrene (CAS RN 50-32-8) ; Benzo[a]pyrene (CAS RN 50-32-8)
• Federal Fiscal Year:
  1981
• Performing Organization:
  University of Cincinnati, Cincinnati, Ohio
• Peer Reviewed:
  True
• Start Date:
  19790301
• Source Full Name:
  Food and Cosmetics Toxicology
• End Date:
  19850228
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7ad28dbf2a6e2a981feb3f5f6eed3e31ad8c17ebb7c7dc1f3f48d4194ee48bfb6b94de0ce753059e9303aa34b009d6f61fd808f9db235456d77fec3c957d777c
• Download URL:
  https://stacks.cdc.gov/view/cdc/184592/cdc_184592_DS1.pdf
• File Type:
  [PDF - 569.57 KB ]