Power considerations in epidemiologic studies of vinyl chloride workers.

Details

• Personal Author:
  Beaumont, James J. ; Breslow NE
• Description:
  Nine retrospective mortality studies of vinyl-chloride (75014) workers were statistically evaluated. The statistical powers of mortality studies were calculated with respect to the liver, brain, and lung sites and plotted on power curves to relate positive and negative findings to power, and to show the variability in powers. The results of the liver and brain cancer studies were consistent with an etiologic role for vinyl-chloride. In the case of lung cancer, two studies with very high power or excess risk yielded negative results indicating that vinyl-chloride was not a lung carcinogen. The authors conclude that power considerations are a useful epidemiologic tool. [Description provided by NIOSH]
• Subjects:
  Epidemiology Manufacturing And Industrial Facilities Mortality Occupational Health Plastics Safety Surveys And Questionnaires Vinyl Chloride
• Keywords:
  Author Keywords: Epidemiologic Methods Brain Neoplasms Chemical-industry-workers Chemical-manufacturing-industry Health-surveys Liver Neoplasms Mortality-rates Respiratory Tract Neoplasms Vinyl Chloride
• ISSN:
  0002-9262
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  114
• Issue:
  5
• NIOSHTIC Number:
  nn:00121087
• Citation:
  Am J Epidemiol 1981 Nov; 114(5):725-734
• Contact Point Address:
  J. J. Beaumont, Industrywide Studies Branch F-8, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226
• CAS Registry Number:
  Vinyl chloride (CAS RN 75-01-4)
• Federal Fiscal Year:
  1982
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Epidemiology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:624de80b06c835c48c9ec6b34e29631389b004bf093784f6718d4a5fff396a30223eb1f81bdaee0c14e28a8f7e852313c4fd385faa6b4c85c62e83092a7a7692
• Download URL:
  https://stacks.cdc.gov/view/cdc/184517/cdc_184517_DS1.pdf
• File Type:
  [PDF - 462.54 KB ]