Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype
Supporting Files
Public Domain
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Jun 2011
Details
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Alternative Title:Emerg Infect Dis
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Personal Author:
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Description:We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
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Subjects:
- Dispatch
- Salmonella
- typhoid fever
- ciprofloxacin
- treatment failure
- gyrB
- bacteria
- antimicrobial resistance
- expedited
- dispatch
- Anti-Bacterial Agents
- Drug Resistance, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Haplotypes
- Humans
- Microbial Sensitivity Tests
- Mutation
- Phenotype
- Quinolones
- Salmonella typhi
- Typhoid Fever
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Source:Emerg Infect Dis. 17(6):1091-1094.
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Document Type:
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Volume:17
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Issue:6
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Download URL:
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File Type:
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Collection(s):
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Main Document Checksum:urn:sha256:e1ea5291a0831749f7b89b51a58e811bce28a2255529f1db200315d905e81a92
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Emerging Infectious Diseases