Factors influencing the measurement of closing volume.
Public Domain
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1975/06/01
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Description:Factors influencing the measurement of closing volume are studied with the single-breath nitrogen test on nine healthy nonsmokers. Time of day, day of the week, and preceding volume history have no effect on either closing volume or alveolar plateau. Slow inspiratory flow results in larger ratio of closing volume to vital capacity, ratio of closing capacity to total lung capacity and change in nitrogen concentration than does fast inspiratory flow. Voluntary regulation of the expiratory flow results in smaller ratios of closing volume to vital capacity and closing volume to vital capacity and ratio of closing capacity to total lung capacity. To obtain uniform, comparable closing volumes, it is suggested that subjects inspire slowly, control expiratory flow voluntarily and not pause between inspiration and expiration. [Description provided by NIOSH]
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ISSN:0003-0805
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Volume:111
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Issue:6
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NIOSHTIC Number:nn:00050876
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Citation:Am Rev Respir Dis 1975 Jun; 111(6):749-754
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Federal Fiscal Year:1975
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Peer Reviewed:True
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Source Full Name:American Review of Respiratory Disease
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Main Document Checksum:urn:sha-512:30e360ff5452738998a735d3dcd7c55e39433a68b72fbc5a8d3272aee5d8a3e44562905b2b72470a9a0204e93e6f43d33a9bb023ee8cd62801d57fe72031b40c
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