Role of relative humidity in the synergistic effect of a sulfur dioxide-aerosol mixture on the lung.

Details

• Personal Author:
  Charlson R ; Frank NR ; McJilton C
• Description:
  Experimental evidence is reported concerning the physicochemical and biological factors involved in the potentiation of the irritant property of sulfur-dioxide (7446095) in combination with an aerosol, in the lungs of the guinea pig. Relative humidity is an important variable for those aerosols capable of absorbing water at relative humidities below 95 percent. The results are in agreement with proposed hypotheses for gas-aerosol synergism. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Irritants Occupational Health Respiratory Tract Diseases Safety Sulfur Compounds Toxicology
• Keywords:
  Air-contaminants Inorganic-gases Interactions NIOSH-Grant NIOSH-Publication Pulmonary-system-disorders Respiratory-irritants Respiratory-system-disorders Sulfur-oxides Time-dose-relationship
• ISSN:
  0036-8075
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  182
• Issue:
  4111
• NIOSHTIC Number:
  nn:00039804
• Citation:
  Science 1973 Nov; 182(4111):503-504
• Contact Point Address:
  Preventive Medicine University of Washington Dept of Preventive Medicine Seattle, Wash 98105
• CAS Registry Number:
  Sulfur dioxide (CAS RN 7446-09-5)
• Federal Fiscal Year:
  1974
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of Washington, Seattle, Washington
• Peer Reviewed:
  True
• Start Date:
  19701001
• Source Full Name:
  Science
• End Date:
  19770331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a75a382007668da4457932a45cf5cf480eb5b5dec7be9bf4b1e78c1b53f4456ce52aa85817320e526b2c0da0daa4ba72764742e67e27f4dda8abd49e16817ff2
• Download URL:
  https://stacks.cdc.gov/view/cdc/184006/cdc_184006_DS1.pdf
• File Type:
  [PDF - 541.31 KB ]