Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Safar, Atheer ; Lennon, Diana ; Stewart, Joanna ; Trenholme, Adrian ; Drinkovic, Dragana ; ... More +
Safar, Atheer ; Lennon, Diana ; Stewart, Joanna ; Trenholme, Adrian ; Drinkovic, Dragana ; Peat, Briar ; Taylor, Susan ; Read, Kerry ; Roberts, Sally ; Voss, Lesley ; Less -
Description:
We aimed to assess the effect of invasive group A streptococcal (GAS) infection and the potential effects of a multivalent GAS vaccine in New Zealand. During January 2005-December 2006, we conducted prospective population-based laboratory surveillance of Auckland residents admitted to all public hospitals with isolation of GAS from normally sterile sites. Using emm typing, we identified 225 persons with confirmed invasive GAS infection (median 53 years of age; range 0-97 years). Overall incidence was 8.1 cases per 100,00 persons per year (20.4/100,000/year for Maori and Pacific Islanders; 24.4/100,000/year for persons >65 years of age; 33/100,000/year for infants <1 year of age). Nearly half (49%) of all cases occurred in Auckland's lowest socioeconomic quintile. Twenty-two persons died, for an overall case-fatality rate of 10% (63% for toxic shock syndrome). Seventy-four percent of patients who died had an underlying condition. To the population in our study, the proposed 26-valent vaccine would provide limited benefit.
Subject:
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Adolescent
Adult
Aged
Aged, 80 And Over
Child
Child, Preschool
Female
Humans
Incidence
Infant
Infant, Newborn
Male
Middle Aged
Research
Risk Factors
Streptococcal Infections
Streptococcal Vaccines
Young Adult

Source:
Emerg Infect Dis. 17(6):983-989. ;
Document Type:
Journal Article ;
Place as Subject:
New Zealand ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:e4f9b4a7f2c7b46fd08966714bd6b3907024f73247d8d6e6f8cbb8a34a97fbc4
File Type:

Supporting Files

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