Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus

Bhoumik, Priyasma; Hughes, Austin L.

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Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus

Supporting Files Public Domain

Nov 2010
By Bhoumik, Priyasma ; Hughes, Austin L.

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Bhoumik, Priyasma ; Hughes, Austin L.
Description:

Sequence analyses show that the outbreak of pandemic (H1N1) 2009 resulted from the spread of a recently derived hemagglutinin through a population of ancient and more diverse neuraminidase segments. This pattern implies reassortment and suggests that the novel form of hemagglutinin conferred a selective advantage.
Subjects:

Evolution, Molecular Gene Expression Regulation, Enzymologic Gene Expression Regulation, Viral Hemagglutinins Humans Influenza, Human Influenza A Virus, H1N1 Subtype Models, Molecular Neuraminidase Pandemics Phylogeny Polymorphism, Genetic Reassortant Viruses Viral Proteins
Source:

Emerg Infect Dis. 16(11):1748-1750.
Document Type:

Journal Article
Volume:

16
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:15a57a9954b9f7c815cf84ef6bfa4cec00ca6c61c3a03d61e1e57381c63e9260
Download URL:

https://stacks.cdc.gov/view/cdc/18280/cdc_18280_DS1.pdf
File Type:

[PDF - 376.36 KB ]

File Language:

English

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