Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus
Published Date:Nov 2010
Source:Emerg Infect Dis. 16(11):1748-1750.
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Viral
Influenza A Virus
Influenza A Virus, H1N1 Subtype
Pandemic (H1N1) 2009 Virus
Description:Sequence analyses show that the outbreak of pandemic (H1N1) 2009 resulted from the spread of a recently derived hemagglutinin through a population of ancient and more diverse neuraminidase segments. This pattern implies reassortment and suggests that the novel form of hemagglutinin conferred a selective advantage.
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