Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Keynan, Yoav ; Juno, Jennifer ; Meyers, Adrienne ; Ball, T. Blake ; Kumar, Anand ; Rubinstein, Ethan ; Fowke, Keith R.
• Description:
  Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.
• Subjects:
  Adult Alleles Critical Illness Disease Outbreaks Female Heterozygote Humans Influenza, Human Influenza A Virus, H1N1 Subtype Male Pandemics Receptors, Ccr5 Sequence Deletion Severity Of Illness Index

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• Source:
  Emerg Infect Dis. 16(10):1621-1622.
• Document Type:
  Journal Article
• Place as Subject:
  Canada
• Location:
  North America
• Volume:
  16
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:25194ba21c9b1ea0b77c9a0ac1fc1f0a9b6f19140df70799c5f1aa7469591a56
• Download URL:
  https://stacks.cdc.gov/view/cdc/18229/cdc_18229_DS1.pdf
• File Type:
  [PDF - 209.24 KB ]