Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Zhang, Yan ; Ding, Zhengrong ; Wang, Huiling ; Li, Liqun ; Pang, Yankun ; ... More +
Zhang, Yan ; Ding, Zhengrong ; Wang, Huiling ; Li, Liqun ; Pang, Yankun ; Brown, Kevin E. ; Xu, Songtao ; Zhu, Zhen ; Rota, Paul A. ; Featherstone, David ; Xu, Wenbo Less -
Description:
To determine the origin of the virus associated with a measles outbreak in Menglian County, Yunnan Province, People's Republic of China, in 2009, we conducted genetic analyses. Phylogenetic analyses based on nucleoprotein (N) and hemagglutinin (H) gene sequences showed that these Menglian viruses were not closely related to sequences of any World Health Organization (WHO) reference strains representing the 23 currently recognized genotypes. The minimum nucleotide divergence between the Menglian viruses and the most closely related reference strain, genotype D7, was 3.3% for the N gene and 3.0% for the H gene. A search of the databases of GenBank, WHO, and the Health Protection Agency Measles Nucleotide Surveillance showed that the Menglian viruses, together with the 2 older non-Menglian viruses, could be members of a new proposed measles genotype, d11. The new genotype designation will allow for better description of measles transmission patterns, especially in the Southeast Asian and Western Pacific regions.
Subjects:
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Adolescent Adult Child Child, Preschool Disease Outbreaks Evolution, Molecular Genetic Variation Hemagglutinins, Viral Humans Infant Measles Molecular Sequence Data Nucleoproteins Phylogeny Research RNA, Viral Sequence Analysis, RNA Viral Proteins
Source:
Emerg Infect Dis. 16(6):943-947.
Document Type:
Journal Article
Place as Subject:
China
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c0f4667e7600cc0f99d817f006ff67400c5e1b39028648c92d071bbee6c77083
Download URL:
https://stacks.cdc.gov/view/cdc/18222/cdc_18222_DS1.pdf
File Type:

Supporting Files

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