Contagious Period for Pandemic (H1N1) 2009

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  De Serres, Gaston ; Rouleau, Isabelle ; Hamelin, Marie-Eve ; Quach, Caroline ; Skowronski, Danuta ; Flamand, Louis ; Boulianne, Nicole ; Li, Yan ; Carbonneau, Julie ; Bourgault, Anne-Marie ; Couillard, Michel ; Charest, Hugues ; Boivin, Guy
• Description:
  We estimated the proportion of persons with pandemic (H1N1) 2009 who were shedding infectious virus at diagnosis and on day 8 of illness. In households with confirmed cases, nasopharyngeal swabs were collected on all members and tested by PCR and virus culture. Of 47 cases confirmed by PCR at <7 days of illness, virus culture was positive in 92% (11/12) of febrile and 63% (22/35) of afebrile persons. Of 43 persons with PCR-confirmed pandemic (H1N1) 2009 from whom a second specimen was collected on day 8, 74% remained PCR positive and 19% were culture positive. If the 73 symptomatic household members without PCR-confirmed illness are assumed to have pandemic (H1N1) 2009, a minimum of 8% (6/73) of case-patients shed replicating virus on day 8. Self-isolation only until fever abates appears insufficient to limit transmission. Self-isolation for a week may be more effective, although some case-patients still would shed infectious virus.
• Subjects:
  Adolescent Adult Child Disease Outbreaks Female Fever Humans Influenza, Human Influenza A Virus, H1N1 Subtype Male Nasopharynx Patient Isolation Rna, Viral Time Factors Virus Cultivation Virus Shedding

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• Source:
  Emerg Infect Dis. 16(5):783-788.
• Document Type:
  Journal Article
• Volume:
  16
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8316c4077587d49160148c8bc61adf6fba04b15712293265b57d29782cd46b1e
• Download URL:
  https://stacks.cdc.gov/view/cdc/18195/cdc_18195_DS1.pdf
• File Type:
  [PDF - 261.69 KB ]