Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Aikembayev, Alim M. ; Lukhnova, Larissa ; Temiraliyeva, Gulnara ; Meka-Mechenko, Tatyana ; Pazylov, Yerlan ; ... More +
Aikembayev, Alim M. ; Lukhnova, Larissa ; Temiraliyeva, Gulnara ; Meka-Mechenko, Tatyana ; Pazylov, Yerlan ; Zakaryan, Sarkis ; Denissov, Georgiy ; Easterday, W. Ryan ; Van Ert, Matthew N. ; Keim, Paul ; Francesconi, Stephen C. ; Blackburn, Jason K. ; Hugh-Jones, Martin ; Hadfield, Ted ; Less -
Description:
To map the distribution of anthrax outbreaks and strain subtypes in Kazakhstan during 1937-2005, we combined geographic information system technology and genetic analysis by using archived cultures and data. Biochemical and genetic tests confirmed the identity of 93 archived cultures in the Kazakhstan National Culture Collection as Bacillus anthracis. Multilocus variable number tandem repeat analysis genotyping identified 12 genotypes. Cluster analysis comparing these genotypes with previously published genotypes indicated that most (n = 78) isolates belonged to the previously described A1.a genetic cluster, 6 isolates belonged to the A3.b cluster, and 2 belonged to the A4 cluster. Two genotypes in the collection appeared to represent novel genetic sublineages; 1 of these isolates was from Krygystan. Our data provide a description of the historical, geographic, and genetic diversity of B. anthracis in this Central Asian region.
Subject:
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Animals
Anthrax
Biological Specimen Banks
Camels
Cattle
Disease Outbreaks
DNA, Bacterial
Dogs
Foxes
Genetic Variation
Geography
Goats
Horses
Humans
Incidence
Mink
Phylogeny
Polymorphism, Single Nucleotide
Sheep
Swine
Time Factors

Source:
Emerg Infect Dis. 16(5):789-796. ;
Document Type:
Journal Article ;
Place as Subject:
Kazakhstan ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:85ca728403eb390cbf95faa96814cb6c7bcbb0334f9855dca811bc7abcbcfc1f
File Type:

Supporting Files

• 	license.txt	txt
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