Historical Distribution and Molecular Diversity of Bacillus anthracis, Kazakhstan

Aikembayev, Alim M.; Lukhnova, Larissa; Temiraliyeva, Gulnara; Meka-Mechenko, Tatyana; Pazylov, Yerlan; Zakaryan, Sarkis; Denissov, Georgiy; Easterday, W. Ryan; Van Ert, Matthew N.; Keim, Paul; Francesconi, Stephen C.; Blackburn, Jason K.; Hugh-Jones, Martin; Hadfield, Ted

i

Historical Distribution and Molecular Diversity of Bacillus anthracis, Kazakhstan

Supporting Files Public Domain

May 2010
By Aikembayev, Alim M. ; Lukhnova, Larissa ; Temiraliyeva, Gulnara ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Aikembayev, Alim M. ; Lukhnova, Larissa ; Temiraliyeva, Gulnara ; Meka-Mechenko, Tatyana ; Pazylov, Yerlan ; Zakaryan, Sarkis ; Denissov, Georgiy ; Easterday, W. Ryan ; Van Ert, Matthew N. ; Keim, Paul ; Francesconi, Stephen C. ; Blackburn, Jason K. ; Hugh-Jones, Martin ; Hadfield, Ted
Description:

To map the distribution of anthrax outbreaks and strain subtypes in Kazakhstan during 1937-2005, we combined geographic information system technology and genetic analysis by using archived cultures and data. Biochemical and genetic tests confirmed the identity of 93 archived cultures in the Kazakhstan National Culture Collection as Bacillus anthracis. Multilocus variable number tandem repeat analysis genotyping identified 12 genotypes. Cluster analysis comparing these genotypes with previously published genotypes indicated that most (n = 78) isolates belonged to the previously described A1.a genetic cluster, 6 isolates belonged to the A3.b cluster, and 2 belonged to the A4 cluster. Two genotypes in the collection appeared to represent novel genetic sublineages; 1 of these isolates was from Krygystan. Our data provide a description of the historical, geographic, and genetic diversity of B. anthracis in this Central Asian region.
Subjects:

Animals Anthrax Biological Specimen Banks Camels Cattle Disease Outbreaks Dna, Bacterial Dogs Foxes Genetic Variation Geography Goats Horses Humans Incidence Mink Phylogeny Polymorphism, Single Nucleotide Sheep Swine Time Factors
Source:

Emerg Infect Dis. 16(5):789-796.
Document Type:

Journal Article
Place as Subject:

Kazakhstan
Volume:

16
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:85ca728403eb390cbf95faa96814cb6c7bcbb0334f9855dca811bc7abcbcfc1f
Download URL:

https://stacks.cdc.gov/view/cdc/18100/cdc_18100_DS1.pdf
File Type:

[PDF - 374.12 KB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.