Genomic Characteristics of Emerging Intraerythrocytic Anaplasma capra and High Prevalence in Goats, China

Lin, Zhe-Tao; Du, Li-Feng; Zhang, Ming-Zhu; Han, Xiao-Yu; Wang, Bai-Hui; Meng, Jiao; Yu, Fu-Xun; Zhou, Xiao-Quan; Wang, Ning; Li, Cheng; Wang, Xiao-Yang; Liu, Jing; Gao, Wan-Ying; Ye, Run-Ze; Xia, Luo-Yuan; Sun, Yi; Jia, Na; Jiang, Jia-Fu; Zhao, Lin; Cui, Xiao-Ming; Zhan, Lin; Cao, Wu-Chun

doi:10.3201/eid2909.230131

i

Genomic Characteristics of Emerging Intraerythrocytic Anaplasma capra and High Prevalence in Goats, China

Supporting Files Public Domain

9 2023
By Lin, Zhe-Tao ; Du, Li-Feng ; Zhang, Ming-Zhu ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Lin, Zhe-Tao ; Du, Li-Feng ; Zhang, Ming-Zhu ; Han, Xiao-Yu ; Wang, Bai-Hui ; Meng, Jiao ; Yu, Fu-Xun ; Zhou, Xiao-Quan ; Wang, Ning ; Li, Cheng ; Wang, Xiao-Yang ; Liu, Jing ; Gao, Wan-Ying ; Ye, Run-Ze ; Xia, Luo-Yuan ; Sun, Yi ; Jia, Na ; Jiang, Jia-Fu ; Zhao, Lin ; Cui, Xiao-Ming ; Zhan, Lin ; Cao, Wu-Chun
Description:

Anaplasma capra is an emerging tickborne human pathogen initially recognized in China in 2015; it has been reported in ticks and in a wide range of domestic and wild animals worldwide. We describe whole-genome sequences of 2 A. capra strains from metagenomic sequencing of purified erythrocytes from infected goats in China. The genome of A. capra was the smallest among members of the genus Anaplasma. The genomes of the 2 A. capra strains contained comparable G+C content and numbers of pseudogenes with intraerythrocytic Anaplasma species. The 2 A. capra strains had 54 unique genes. The prevalence of A. capra was high among goats in the 2 endemic areas. Phylogenetic analyses revealed that the A. capra strains detected in this study were basically classified into 2 subclusters with those previously detected in Asia. Our findings clarify details of the genomic characteristics of A. capra and shed light on its genetic diversity.
Subjects:

Anaplasma Animals Genomics Goats Humans Phylogeny Prevalence
Keywords:

Anaplasma Capra Bacteria Bacterial Infection China Goats Phylogenetic Analysis Prevalence Tickborne Diseases Vector-borne Infections Whole-genome Analysis Zoonoses
Source:

Emerg Infect Dis. 2023; 29(9):1780-1788
Pubmed ID:

37610104
Pubmed Central ID:

PMC10461651
Document Type:

Journal Article
Place as Subject:

China
Volume:

29
Issue:

9
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:1421cc326860e63341d3c2cf894e1301529d001119e8b64a836bb0a7078870cd
Download URL:

https://stacks.cdc.gov/view/cdc/133573/cdc_133573_DS1.pdf
File Type:

[PDF - 3.35 MB ]

File Language:

English

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