Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus

Drexler, Jan Felix; Helmer, Angelika; Kirberg, Heike; Reber, Ulrike; Panning, Marcus; Müller, Marcel; Höfling, Katja; Matz, Bertfried; Drosten, Christian; Eis-Hübinger, Anna Maria

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Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus

Supporting Files Public Domain

Oct 2009
By Drexler, Jan Felix ; Helmer, Angelika ; Kirberg, Heike ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Drexler, Jan Felix ; Helmer, Angelika ; Kirberg, Heike ; Reber, Ulrike ; Panning, Marcus ; Müller, Marcel ; Höfling, Katja ; Matz, Bertfried ; Drosten, Christian ; Eis-Hübinger, Anna Maria
Description:

Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.
Subjects:

Adolescent Adult Antigens, Viral Child Child, Preschool Disease Outbreaks False Negative Reactions Humans Infant Influenza, Human Influenza A Virus, H1N1 Subtype Polymerase Chain Reaction Sensitivity And Specificity Serologic Tests Young Adult
Source:

Emerg Infect Dis. 15(10):1662-1664.
Document Type:

Journal Article
Place as Subject:

Germany
Location:

Europe
Volume:

15
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:98a1fd024bca02601fb6e0f55f828b88da9c439ea51a51e35f46982370e65b80
Download URL:

https://stacks.cdc.gov/view/cdc/18048/cdc_18048_DS1.pdf
File Type:

[PDF - 429.68 KB ]

File Language:

English

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