Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus
Published Date:Oct 2009
Source:Emerg Infect Dis. 15(10):1662-1664.
False Negative Reactions
Influenza A Pandemic (H1N1) 2009 Virus
Influenza A Virus, H1N1 Subtype
Influenza Virus A (H1N1)
Polymerase Chain Reaction
Rapid Antigen-based Test
Sensitivity And Specificity
Description:Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.
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