Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Ilyushina, Natalia A. ; Kim, Jeong-Ki ; Negovetich, Nicholas J. ; Choi, Young-Ki ; Lang, Victoria ; Bovin, Nicolai V. ; Forrest, Heather L. ; Song, Min-Suk ; Pascua, Philippe Noriel Q. ; Kim, Chul-Joong ; Webster, Robert G. ; Webby, Richard J.
• Description:
  We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus-like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indicating longstanding adaptation to mammals.
• Subjects:
  Animals Disease Outbreaks Disease Reservoirs Hemagglutinin Glycoproteins, Influenza Virus Humans Influenza A Virus, H1N1 Subtype Mammals Pandemics Phylogeny Quail Swine Swine Diseases Virus Replication

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• Source:
  Emerg Infect Dis. 16(2):314-317.
• Document Type:
  Journal Article
• Volume:
  16
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:0bb7e6229d571de883f236996870e227b853d5b094167544ae4beb632cbded84
• Download URL:
  https://stacks.cdc.gov/view/cdc/18040/cdc_18040_DS1.pdf
• File Type:
  [PDF - 275.98 KB ]