Worldwide Dissemination of the blaOXA-23 Carbapenemase Gene of Acinetobacter baumannii1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Mugnier, Pauline D. ; Poirel, Laurent ; Naas, Thierry ; Nordmann, Patrice
• Description:
  To assess dissemination of OXA-23-producing strains of Acinetobacter baumannii, we obtained 20 carbapenem-resistant, OXA-23-producing isolates from different regions. Their clonal relationship was assessed by pulsed-field gel electrophoresis and multilocus sequence typing. We identified 8 sequence types, including 4 novel types. All except 2 strains belonged to 2 main European clonal lineages. The blaOXA-23 gene was either located on the chromosome or on plasmids and associated with 4 genetic structures.
• Subjects:
  Acinetobacter Infections Beta-Lactamases Beta-Lactam Resistance Blotting, Southern Cloning, Molecular Electrophoresis, Gel, Pulsed-Field Genes, Bacterial Gene Transfer, Horizontal Humans Microbial Sensitivity Tests Molecular Sequence Data Research

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• Source:
  Emerg Infect Dis. 16(1):35-40.
• Document Type:
  Journal Article
• Volume:
  16
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:368e785f830de7e34c2eca73ed65d69d9d4afc89a69229c5535e3c99891706c8
• Download URL:
  https://stacks.cdc.gov/view/cdc/17979/cdc_17979_DS1.pdf
• File Type:
  [PDF - 275.79 KB ]