Worldwide Dissemination of the blaOXA-23 Carbapenemase Gene of Acinetobacter baumannii1

Mugnier, Pauline D.; Poirel, Laurent; Naas, Thierry; Nordmann, Patrice

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Worldwide Dissemination of the blaOXA-23 Carbapenemase Gene of Acinetobacter baumannii1

Published Date:

Jan 2010

Source:

Emerg Infect Dis. 16(1):35-40.

[PDF - 275.79 KB]

Details:

Personal Authors:

Mugnier, Pauline D. ; Poirel, Laurent ; Naas, Thierry ; Nordmann, Patrice ;

Keywords:

[+]

Description:

To assess dissemination of OXA-23-producing strains of Acinetobacter baumannii, we obtained 20 carbapenem-resistant, OXA-23-producing isolates from different regions. Their clonal relationship was assessed by pulsed-field gel electrophoresis and multilocus sequence typing. We identified 8 sequence types, including 4 novel types. All except 2 strains belonged to 2 main European clonal lineages. The blaOXA-23 gene was either located on the chromosome or on plasmids and associated with 4 genetic structures.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

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