Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Reißmann, Silvana ; Friedrichs, Claudia ; Rajkumari, Reena ; Itzek, Andreas ; Fulde, Marcus ; ... More +
Reißmann, Silvana ; Friedrichs, Claudia ; Rajkumari, Reena ; Itzek, Andreas ; Fulde, Marcus ; Rodloff, Arne C. ; Brahmadathan, Kootallur N. ; Chhatwal, Gursharan S. ; Nitsche-Schmitz, D. Patric ; Less -
Description:
Vellore, a region in southern India, has a high incidence of severe human infections with Beta-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006-2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.
Subject:
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DNA, Bacterial
Genes, Bacterial
Genetic Markers
Humans
Open Reading Frames
Polymerase Chain Reaction
Research
RNA, Ribosomal, 16S
Sequence Analysis, DNA
Streptococcal Infections
Streptococcus
Streptococcus Constellatus
Virulence Factors

Source:
Emerg Infect Dis. 16(4):656-663. ;
Document Type:
Journal Article ;
Place as Subject:
India ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:ac47c23cdb5fc64c9d6a0b178fc2693d05ab45a841077662cf198baccbe49ac9
File Type:

Supporting Files

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