Distant Relatives of Severe Acute Respiratory Syndrome Coronavirus and Close Relatives of Human Coronavirus 229E in Bats, Ghana

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Pfefferle, Susanne ; Oppong, Samuel ; Drexler, Jan Felix ; Gloza-Rausch, Florian ; Ipsen, Anne ; Seebens, Antje ; Müller, Marcel A. ; Annan, Augustina ; Vallo, Peter ; Adu-Sarkodie, Yaw ; Kruppa, Thomas F. ; Drosten, Christian
  More +
• Description:
  We tested 12 bat species in Ghana for coronavirus (CoV) RNA. The virus prevalence in insectivorous bats (n = 123) was 9.76%. CoV was not detected in 212 fecal samples from Eidolon helvum fruit bats. Leaf-nosed bats pertaining to Hipposideros ruber by morphology had group 1 and group 2 CoVs. Virus concentrations were < or =45,000 copies/100 mg of bat feces. The diversified group 1 CoV shared a common ancestor with the human common cold virus hCoV-229E but not with hCoV-NL63, disputing hypotheses of common human descent. The most recent common ancestor of hCoV-229E and GhanaBt-CoVGrp1 existed in approximately 1686-1800 ad. The GhanaBt-CoVGrp2 shared an old ancestor (approximately 2,400 years) with the severe acute respiratory syndrome-like group of CoV.
• Subjects:
  • Animals
  • Chiroptera
  • Coronavirus
  • Coronavirus 229E, Human
  • Feces
  • Female
  • Humans
  • Male
  • Molecular Sequence Data
  • Phylogeny
  More +
• Source:
  Emerg Infect Dis. 15(9):1377-1384.
• Document Type:
  Journal Article
• Place as Subject:
  Ghana
• Location:
  Africa
• Volume:
  15
• Issue:
  9
• Download URL:
  https://stacks.cdc.gov/view/cdc/17856/cdc_17856_DS1.pdf
• File Type:
  [PDF - 682.43 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:22666ddefafb4923333a85a3ebded2f3c8fc03ba9840cd925734e55ea8ff6846