Acute Encephalopathy Associated with Influenza A Infection in Adults

Lee, Nelson; Wong, Chun Kwok; Chan, Paul K.S.; Lindegardh, Niklas; White, Nicholas J.; Hayden, Frederick G.; Wong, Edward H.C.; Wong, Ka Shing; Cockram, Clive S.; Sung, Joseph J.Y.; Hui, David S.C.

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Acute Encephalopathy Associated with Influenza A Infection in Adults

Jan 2010
By Lee, Nelson ; Wong, Chun Kwok ; Chan, Paul K.S. ; ...
Source: Emerg Infect Dis. 16(1):139-142.

[PDF-199.31 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Lee, Nelson ; Wong, Chun Kwok ; Chan, Paul K.S. ; Lindegardh, Niklas ; White, Nicholas J. ; ... More +

Lee, Nelson ; Wong, Chun Kwok ; Chan, Paul K.S. ; Lindegardh, Niklas ; White, Nicholas J. ; Hayden, Frederick G. ; Wong, Edward H.C. ; Wong, Ka Shing ; Cockram, Clive S. ; Sung, Joseph J.Y. ; Hui, David S.C. Less -
Description:

We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.
Subjects:

[+]

Adults Aged Aged, 80 And Over Cytokine Cytokines Dispatch Encephalitis, Viral Encephalopathy Female Humans Infection Influenza Influenza, Human Influenza A Influenza A Virus Male Virus
Source:

Emerg Infect Dis. 16(1):139-142.
Document Type:

Journal Article
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:0e0856368ee2629b7b5b5e14bae9e569b92de2980ec895531ba4c3480257e9f7
Download URL:

https://stacks.cdc.gov/view/cdc/17821/cdc_17821_DS1.pdf
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	09-0077_finalD.nxml	txt
	09-0077_Techapp-s1.pdf	pdf
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