Meningitis and a Febrile Vomiting illness Caused by Echovirus Type 4, Northern Territory, Australia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Markey, Peter G. ; Davis, Joshua S. ; Harnett, Gerry B. ; Williams, Simon H. ; Speers, David J.
• Description:
  In July 2007, a cluster of meningitis cases caused by an echovirus 4 strain was detected in 1 indigenous community in the Top End of the Northern Territory of Australia. Illness was characterized by fever, vomiting, and headache. Over the next 4 months, additional cases of meningitis and the fever and vomiting syndrome emerged in other indigenous communities and subsequently in the major urban center of Darwin. We describe the epidemiology of 95 laboratory-confirmed meningitis cases and conclude that the epidemic fever and vomiting syndrome was caused by the same enterovirus. Nucleotide sequencing of the whole genome verified this enterovirus (AUS250G) as a strain of echovirus type 4. Viral protein 1 nucleotide sequencing demonstrated 96% homology with an echovirus 4 strain responsible for a large outbreak of meningitis in the Yanbian Prefecture of China in 1996.
• Subjects:
  Adolescent Adult Base Sequence Child Child, Preschool Disease Outbreaks Echovirus Infections Enterovirus B, Human Female Humans Infant Infant, Newborn Male Meningitis, Viral Middle Aged Molecular Sequence Data Native Hawaiian Or Other Pacific Islander Northern Territory Phylogeny Vomiting Young Adult

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• Source:
  Emerg Infect Dis. 16(1):63-68.
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Location:
  Oceania
• Volume:
  16
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:619695e2eb452435a1e95adcaf68987dab08591ef40b18eb70678b13b9465145
• Download URL:
  https://stacks.cdc.gov/view/cdc/17775/cdc_17775_DS1.pdf
• File Type:
  [PDF - 318.35 KB ]