Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Andernach, Iris E. ; Nolte, Claudine ; Pape, Jean W. ; Muller, Claude P.
Andernach, Iris E. ; Nolte, Claudine ; Pape, Jean W. ; Muller, Claude P. Less -
Description:
In Haiti, >90% of the population descended from African slaves. Of 7,147 Haitian pregnant women sampled, 44% of hepatitis B virus (HBV) infections were caused by genotype A1, which today is found mainly in eastern Africa. Twenty percent belong to a rare subgenotype, A5, which has been found only in the former Bight of Benin, a former primary slave trading post. Haitian A subgenotypes appear to have separated early from the African subgenotypes; the most prevalent genotype and subgenotype in West Africa today (E and A3, respectively) are rare in Haiti. This difference indicates that the dominant subgenotypes in Africa emerged in the general population only after the slave trade and explains the low genetic diversity of genotype E. The high prevalence of HBV genotype E in much of Africa further suggests that HBV hyperendemicity is a recent phenomenon, probably resulting from extensive use of unsafe needles.
Subject:
[+]
Communicable Diseases, Emerging
DOI: 10.3201/eid1508.081642
Female
Genotype
Hepatitis B
Hepatitis B Virus
Humans
Molecular Epidemiology
Phylogeny
Pregnancy
Pregnancy Complications, Infectious
Prevalence
Recombination, Genetic
Research
Social Problems
Transatlantic Slave Trade
Viruses

Source:
Emerg Infect Dis. 15(8):1222-1228.
Document Type:
Journal Article
Place as Subject:
Haiti ; Caribbean Region ; Africa
Haiti ; Caribbean Region ; Africa Less -
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:dcf5517f09de53431169a837f8e7382cb937ab1a91a7b1af38cdc80a02965f3e
File Type:

Supporting Files

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