Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Mendes, Marcia O.; Moraes, Mario A.P.; Renoiner, Ernesto I.M.; Dantas, Marta H.P.; Lanzieri, Tatiania M.; ... More +
Mendes, Marcia O.; Moraes, Mario A.P.; Renoiner, Ernesto I.M.; Dantas, Marta H.P.; Lanzieri, Tatiania M.; Fonseca, Carlos F.; Luna, Expedito J.A.; Hatch, Douglas L.; Less -
Description:
We conducted an epidemiologic investigation of an outbreak of ocular disease among children to determine whether the disease was linked to Emmonsia sp., a rarely-reported fungus and an agent of adiaspiromycosis. Using an unmatched case-control study design, we compared case-patients with asymptomatic controls randomly selected from the population. Scleral biopsies were analyzed microscopically. Of 5,084 children examined, 99 case-patients were identified; mean age (+1 SD) was 11.0 +/- 4.4 years. Symptoms included photophobia (57%), ocular pain (42%), and blurred vision (40%). In the multivariate analysis, risk factors included diving in the Araguaia River (odds ratio 5.2; 95% confidence interval 2.4-12.0). Microscopy identified foreign bodies consistent with adiaconidia. This outbreak probably resulted from foreign-body-type reactions to adiaspiromycosis conidia after initial irritation caused by conjunctival contact with spicules of sponges in the river. Symptomatic children responded to corticosteroid treatment. Adiaspiromycosis is a preventable cause of ocular disease in the Amazon region.
Subject:
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Adolescent
Animals
Case-Control Studies
Child
Child, Preschool
Chrysosporium
Communicable Diseases, Emerging
Disease Outbreaks
Eye Infections, Fungal
Female
Fresh Water
Humans
Infant
Male
Porifera
Research
Uveitis, Anterior
Young Adult

Source:
Emerg Infect Dis. 15(4):633-639.;
Document Type:
Journal Article;
Place as Subject:
Brazil;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:7b5441d4dbc41e0cda7321f999fa3cbeb505acd9ff76a4c54b3a900df6c82421
File Type:

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