Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

Shah, Naman K.; Alker, Alisa P.; Sem, Rithy; Susanti, Agustina Ika; Muth, Sinuon; Maguire, Jason D.; Duong, Socheat; Ariey, Frederic; Meshnick, Steven R.; Wongsrichanalai, Chansuda

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Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

Published Date:

Oct 2008

Source:

Emerg Infect Dis. 14(10):1637-1640

Language:

English

[PDF-275.33 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Shah, Naman K. ; Alker, Alisa P. ; Sem, Rithy ; Susanti, Agustina Ika ; Muth, Sinuon ; ... More ▼

Description:

We conducted surveillance for multidrug-resistant Plasmodium falciparum in Cambodia during 2004-2006 by assessing molecular changes in pfmdr1. The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate-mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.

Subject:

[+]

Pubmed ID:

18826834

Pubmed Central ID:

PMC2609877

Document Type:

Journal Article

Funding:

D43 TW007402/TW/FIC NIH HHS/United States ; PD 5D43TW007402-02/TW/FIC NIH HHS/United States ;

Place as Subject:

Cambodia

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

File Type:

Supporting Files:

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Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

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