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Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia
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Oct 2008
Source: Emerg Infect Dis. 14(10):1637-1640
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Alternative Title:Emerg Infect Dis
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Description:We conducted surveillance for multidrug-resistant Plasmodium falciparum in Cambodia during 2004-2006 by assessing molecular changes in pfmdr1. The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate-mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.
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Pubmed ID:18826834
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Pubmed Central ID:PMC2609877
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