Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Kalthoff, Donata ; Breithaupt, Angele ; Teifke, Jens P. ; Globig, Anja ; Harder, Timm ; Mettenleiter, Thomas C. ; Beer, Martin
• Description:
  Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity.
• Subjects:
  Animals Anseriformes Antibodies, Viral Avian Influenza Brain Dispatch Epidemiology Eye Female Influenza A Virus, H5N1 Subtype Influenza In Birds Liver Male Mute Swan Pathogenicity Preexposure Immunity RNA, Viral Skin Subtype H5N1 Time Factors Viral Load Virus Replication Virus Shedding

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• Source:
  Emerg Infect Dis. 14(8):1267-1270.
• Document Type:
  Journal Article
• Volume:
  14
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:9018163a8fb543ce4b807a75e7cd7a615d63d3e35624126b1a455855fc161556
• Download URL:
  https://stacks.cdc.gov/view/cdc/17191/cdc_17191_DS1.pdf
• File Type:
  [PDF - 356.71 KB ]